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Protein : FBpp0310747 D. melanogaster

Primary Accession  ? Q24167 Organism . Name  Drosophila melanogaster
MD5 Checksum  3d88b13d949e86ff5af8928e16bd83d3 UniProt Accession  Q24167
UniProt Name  SIMA_DROME Is UniProt Canonical  true
Is Fragment  false Length  1507
Molecular Weight  165824 Name  Protein similar
Secondary Identifier  FBpp0310747

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Uni Prot Comments Displayer

Protein Sequence Displayer


1 Genes

DB identifier Secondary Identifier Symbol Name Source Organism
FBgn0266411 CG45051 sima similar FlyBase D. melanogaster


Protein --> Gene + chromosomal location and length of the gene.


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3 Synonyms

0 Components

2 Cross References

Source . Name

Subject . Primary Identifier
Dm.6953 UniGene FBpp0310747
NP_524584.2 RefSeq FBpp0310747

3 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set
Reactome data set  

0 Ec Numbers

1 Locations

Located On . Primary Identifier
Start End Strand
3R 25884647 25946477 1

28 Pathways

Identifier Name
133121 Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
133037 Regulation of Gene Expression by Hypoxia-inducible Factor
125904 Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
29934 Circadian Clock
154437 Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
144067 Cellular responses to stress
145232 Cellular response to hypoxia
120472 Signaling by NOTCH4
162718 Signaling by NOTCH1 HD Domain Mutants in Cancer
162388 Signaling by NOTCH1 PEST Domain Mutants in Cancer
162365 Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer
162349 FBXW7 Mutants and NOTCH1 in Cancer
162508 Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant
158569 A third proteolytic cleavage releases NICD
162622 Signaling by NOTCH1 in Cancer
118381 Disease
120403 Signaling by NOTCH3
162544 NOTCH2 Activation and Transmission of Signal to the Nucleus
120634 NOTCH1 Intracellular Domain Regulates Transcription
120586 Signaling by NOTCH2
120524 Signaling by NOTCH1
120582 Activated NOTCH1 Transmits Signal to the Nucleus
152825 Pre-NOTCH Processing in the Endoplasmic Reticulum
120528 Pre-NOTCH Processing in Golgi
78520 Signaling by NOTCH
120456 Pre-NOTCH Expression and Processing
97910 Signaling Pathways
84305 NICD traffics to nucleus

5 Protein Domains

DB identifier Name Short Name Type
IPR001610 PAC motif PAC Repeat
IPR000014 PAS domain PAS Domain
IPR011598 Myc-type, basic helix-loop-helix (bHLH) domain bHLH_dom Domain
IPR013767 PAS fold PAS_fold Domain
IPR013655 PAS fold-3 PAS_fold_3 Domain

1 Transcripts

DB identifier Gene
FBtr0344374 sima