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GO Term : GO:0046849 bone remodeling GO
Namespace  biological_process Obsolete  false
description  The continuous turnover of bone matrix and mineral that involves first, an increase in resorption (osteoclastic activity) and later, reactive bone formation (osteoblastic activity). The process of bone remodeling takes place in the adult skeleton at discrete foci. The process ensures the mechanical integrity of the skeleton throughout life and plays an important role in calcium homeostasis. An imbalance in the regulation of bone resorption and bone formation results in many of the metabolic bone diseases, such as osteoporosis.
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2 Data Sets

Name URL
GO Annotation from FlyBase  
InterPro GO Annotation data set  

1 Ontology

Name
GO

4 Ontology Annotations


Subject . Secondary Identifier
Subject . Name
Subject . Symbol
Ontology Term . Identifier
Ontology Term . Name
CG10961 TNF-receptor-associated factor 6 Traf6 GO:0046849 bone remodeling
5-Hydroxytryptamine 1B receptor   GO:0046849 bone remodeling
Secreted phosphoprotein 24   GO:0046849 bone remodeling
TNF receptor-associated factor 6   GO:0046849 bone remodeling

6 Parents

Identifier Name
GO:0044699 single-organism process
GO:0008150 biological_process
GO:0044707 single-multicellular organism process
GO:0032501 multicellular organismal process
GO:0048771 tissue remodeling
GO:0046849 bone remodeling

17 Relations

Relationship
Parent Term . Name
Parent Term . Identifier
Child Term . Name
Child Term . Identifier
part_of bone remodeling GO:0046849 ossification involved in bone remodeling GO:0043932
regulates bone remodeling GO:0046849 regulation of bone resorption GO:0045124
part_of bone remodeling GO:0046849 bone resorption GO:0045453
negatively regulates bone remodeling GO:0046849 negative regulation of bone resorption GO:0045779
regulates bone remodeling GO:0046849 negative regulation of bone resorption GO:0045779
positively regulates bone remodeling GO:0046849 positive regulation of bone resorption GO:0045780
regulates bone remodeling GO:0046849 positive regulation of bone resorption GO:0045780
is_a tissue remodeling GO:0048771 bone remodeling GO:0046849
is_a multicellular organismal process GO:0032501 bone remodeling GO:0046849
is_a single-organism process GO:0044699 bone remodeling GO:0046849
is_a biological_process GO:0008150 bone remodeling GO:0046849
is_a single-multicellular organism process GO:0044707 bone remodeling GO:0046849
regulates bone remodeling GO:0046849 regulation of bone remodeling GO:0046850
negatively regulates bone remodeling GO:0046849 negative regulation of bone remodeling GO:0046851
regulates bone remodeling GO:0046849 negative regulation of bone remodeling GO:0046851
positively regulates bone remodeling GO:0046849 positive regulation of bone remodeling GO:0046852
regulates bone remodeling GO:0046849 positive regulation of bone remodeling GO:0046852

1 Synonyms

Name Type
bone remodelling exact_synonym




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