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GO Term : GO:0038061 NIK/NF-kappaB signaling GO

Namespace  biological_process Obsolete  false
description  The process in which a signal is passed on to downstream components within the cell through the NIK-dependent processing and activation of NF-KappaB. Begins with activation of the NF-KappaB-inducing kinase (NIK), which in turn phosphorylates and activates IkappaB kinase alpha (IKKalpha). IKKalpha phosphorylates the NF-Kappa B2 protein (p100) leading to p100 processing and release of an active NF-KappaB (p52).

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

15 Parents

Identifier Name
GO:0044699 single-organism process
GO:0009987 cellular process
GO:0008150 biological_process
GO:0044763 single-organism cellular process
GO:0050896 response to stimulus
GO:0051716 cellular response to stimulus
GO:0065007 biological regulation
GO:0050794 regulation of cellular process
GO:0050789 regulation of biological process
GO:0007154 cell communication
GO:0007165 signal transduction
GO:0044700 single organism signaling
GO:0023052 signaling
GO:0035556 intracellular signal transduction
GO:0038061 NIK/NF-kappaB signaling

25 Relations

Relationship
Parent Term . Name

Parent Term . Identifier

Child Term . Name

Child Term . Identifier
part_of NIK/NF-kappaB signaling GO:0038061 activation of NF-kappaB-inducing kinase activity GO:0007250
regulates NIK/NF-kappaB signaling GO:0038061 activation of NF-kappaB-inducing kinase activity GO:0007250
is_a intracellular signal transduction GO:0035556 NIK/NF-kappaB signaling GO:0038061
part_of signaling GO:0023052 NIK/NF-kappaB signaling GO:0038061
is_a response to stimulus GO:0050896 NIK/NF-kappaB signaling GO:0038061
part_of biological_process GO:0008150 NIK/NF-kappaB signaling GO:0038061
regulates biological_process GO:0008150 NIK/NF-kappaB signaling GO:0038061
part_of cell communication GO:0007154 NIK/NF-kappaB signaling GO:0038061
part_of single-organism cellular process GO:0044763 NIK/NF-kappaB signaling GO:0038061
is_a cellular response to stimulus GO:0051716 NIK/NF-kappaB signaling GO:0038061
part_of cellular process GO:0009987 NIK/NF-kappaB signaling GO:0038061
is_a biological_process GO:0008150 NIK/NF-kappaB signaling GO:0038061
is_a biological regulation GO:0065007 NIK/NF-kappaB signaling GO:0038061
regulates cellular process GO:0009987 NIK/NF-kappaB signaling GO:0038061
part_of single organism signaling GO:0044700 NIK/NF-kappaB signaling GO:0038061
is_a signal transduction GO:0007165 NIK/NF-kappaB signaling GO:0038061
is_a cellular process GO:0009987 NIK/NF-kappaB signaling GO:0038061
is_a regulation of cellular process GO:0050794 NIK/NF-kappaB signaling GO:0038061
is_a regulation of biological process GO:0050789 NIK/NF-kappaB signaling GO:0038061
part_of single-organism process GO:0044699 NIK/NF-kappaB signaling GO:0038061
regulates NIK/NF-kappaB signaling GO:0038061 regulation of NIK/NF-kappaB signaling GO:1901222
negatively regulates NIK/NF-kappaB signaling GO:0038061 negative regulation of NIK/NF-kappaB signaling GO:1901223
regulates NIK/NF-kappaB signaling GO:0038061 negative regulation of NIK/NF-kappaB signaling GO:1901223
positively regulates NIK/NF-kappaB signaling GO:0038061 positive regulation of NIK/NF-kappaB signaling GO:1901224
regulates NIK/NF-kappaB signaling GO:0038061 positive regulation of NIK/NF-kappaB signaling GO:1901224

6 Synonyms

Name Type
non-canonical NF-KB signaling broad_synonym
NIK/NF-kappaB signal transduction exact_synonym
NIK/NF-kappaB cascade related_synonym
p52-dependent NF-kappaB signaling narrow_synonym
noncanonical nuclear factor kappaB (NF-kappaB) pathway broad_synonym
noncanonical NF-kappaB signaling broad_synonym