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GO Term : GO:0072376 protein activation cascade GO

Namespace  biological_process Obsolete  false
description  A response to a stimulus that consists of a sequential series of modifications to a set of proteins where the product of one reaction acts catalytically in the following reaction. The magnitude of the response is typically amplified at each successive step in the cascade. Modifications typically include proteolysis or covalent modification, and may also include binding events.

0 Data Sets

1 Ontology

Name
GO

0 Ontology Annotations

10 Parents

Identifier Name
GO:0044699 single-organism process
GO:0008150 biological_process
GO:0044238 primary metabolic process
GO:0050896 response to stimulus
GO:0071704 organic substance metabolic process
GO:0043170 macromolecule metabolic process
GO:0044710 single-organism metabolic process
GO:0008152 metabolic process
GO:0019538 protein metabolic process
GO:0072376 protein activation cascade

102 Relations

Relationship
Parent Term . Name

Parent Term . Identifier

Child Term . Name

Child Term . Identifier
is_a protein activation cascade GO:0072376 complement activation, lectin pathway GO:0001867
regulates protein activation cascade GO:0072376 regulation of complement activation, lectin pathway GO:0001868
regulates protein activation cascade GO:0072376 negative regulation of complement activation, lectin pathway GO:0001869
negatively regulates protein activation cascade GO:0072376 negative regulation of complement activation, lectin pathway GO:0001869
regulates protein activation cascade GO:0072376 positive regulation of complement activation, lectin pathway GO:0001870
positively regulates protein activation cascade GO:0072376 positive regulation of complement activation, lectin pathway GO:0001870
is_a protein activation cascade GO:0072376 activation of membrane attack complex GO:0001905
regulates protein activation cascade GO:0072376 regulation of activation of membrane attack complex GO:0001969
positively regulates protein activation cascade GO:0072376 positive regulation of activation of membrane attack complex GO:0001970
regulates protein activation cascade GO:0072376 positive regulation of activation of membrane attack complex GO:0001970
negatively regulates protein activation cascade GO:0072376 negative regulation of activation of membrane attack complex GO:0001971
regulates protein activation cascade GO:0072376 negative regulation of activation of membrane attack complex GO:0001971
is_a protein activation cascade GO:0072376 kinin cascade GO:0002254
is_a protein activation cascade GO:0072376 tissue kallikrein-kinin cascade GO:0002255
regulates protein activation cascade GO:0072376 regulation of kinin cascade GO:0002256
negatively regulates protein activation cascade GO:0072376 negative regulation of kinin cascade GO:0002257
regulates protein activation cascade GO:0072376 negative regulation of kinin cascade GO:0002257
regulates protein activation cascade GO:0072376 positive regulation of kinin cascade GO:0002258
positively regulates protein activation cascade GO:0072376 positive regulation of kinin cascade GO:0002258
is_a protein activation cascade GO:0072376 plasma kallikrein-kinin cascade GO:0002353
regulates protein activation cascade GO:0072376 regulation of tissue kallikrein-kinin cascade GO:0002382
regulates protein activation cascade GO:0072376 regulation of plasma kallikrein-kinin cascade GO:0002529
part_of protein activation cascade GO:0072376 Factor XII activation GO:0002542
regulates protein activation cascade GO:0072376 negative regulation of tissue kallikrein-kinin cascade GO:0002546
negatively regulates protein activation cascade GO:0072376 negative regulation of tissue kallikrein-kinin cascade GO:0002546
regulates protein activation cascade GO:0072376 positive regulation of tissue kallikrein-kinin cascade GO:0002547
positively regulates protein activation cascade GO:0072376 positive regulation of tissue kallikrein-kinin cascade GO:0002547
regulates protein activation cascade GO:0072376 negative regulation of plasma kallikrein-kinin cascade GO:0002549
negatively regulates protein activation cascade GO:0072376 negative regulation of plasma kallikrein-kinin cascade GO:0002549
positively regulates protein activation cascade GO:0072376 positive regulation of plasma kallikrein-kinin cascade GO:0002550

2 Synonyms

Name Type
protein activitory cascade exact_synonym
protein activation pathway exact_synonym