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GO Term : GO:0006956 complement activation GO

Namespace  biological_process Obsolete  false
description  Any process involved in the activation of any of the steps of the complement cascade, which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes; the initial steps of complement activation involve one of three pathways, the classical pathway, the alternative pathway, and the lectin pathway, all of which lead to the terminal complement pathway.

1 Data Sets

Name URL
InterPro GO Annotation data set  

1 Ontology

Name
GO

3 Ontology Annotations


Subject . Secondary Identifier

Subject . Name

Subject . Symbol

Ontology Term . Identifier

Ontology Term . Name
Anaphylatoxin, complement system domain   GO:0006956 complement activation
Complement B/C2   GO:0006956 complement activation
Peptidase S1A, complement C1r/C1S/mannan-binding   GO:0006956 complement activation

25 Parents

Identifier Name
GO:0044699 single-organism process
GO:0008150 biological_process
GO:0044238 primary metabolic process
GO:0050896 response to stimulus
GO:0071704 organic substance metabolic process
GO:0043170 macromolecule metabolic process
GO:0044710 single-organism metabolic process
GO:0008152 metabolic process
GO:0065007 biological regulation
GO:0050789 regulation of biological process
GO:0019538 protein metabolic process
GO:0048583 regulation of response to stimulus
GO:0048518 positive regulation of biological process
GO:0048584 positive regulation of response to stimulus
GO:0002376 immune system process
GO:0006955 immune response
GO:0002252 immune effector process
GO:0002682 regulation of immune system process
GO:0050776 regulation of immune response
GO:0002684 positive regulation of immune system process
GO:0050778 positive regulation of immune response
GO:0006956 complement activation
GO:0006959 humoral immune response
GO:0002253 activation of immune response
GO:0072376 protein activation cascade

78 Relations

Relationship
Parent Term . Name

Parent Term . Identifier

Child Term . Name

Child Term . Identifier
is_a complement activation GO:0006956 complement activation, lectin pathway GO:0001867
regulates complement activation GO:0006956 regulation of complement activation, lectin pathway GO:0001868
regulates complement activation GO:0006956 negative regulation of complement activation, lectin pathway GO:0001869
negatively regulates complement activation GO:0006956 negative regulation of complement activation, lectin pathway GO:0001869
regulates complement activation GO:0006956 positive regulation of complement activation, lectin pathway GO:0001870
positively regulates complement activation GO:0006956 positive regulation of complement activation, lectin pathway GO:0001870
is_a complement activation GO:0006956 activation of membrane attack complex GO:0001905
regulates complement activation GO:0006956 regulation of activation of membrane attack complex GO:0001969
positively regulates complement activation GO:0006956 positive regulation of activation of membrane attack complex GO:0001970
regulates complement activation GO:0006956 positive regulation of activation of membrane attack complex GO:0001970
negatively regulates complement activation GO:0006956 negative regulation of activation of membrane attack complex GO:0001971
regulates complement activation GO:0006956 negative regulation of activation of membrane attack complex GO:0001971
is_a activation of immune response GO:0002253 complement activation GO:0006956
is_a immune effector process GO:0002252 complement activation GO:0006956
is_a humoral immune response GO:0006959 complement activation GO:0006956
is_a protein activation cascade GO:0072376 complement activation GO:0006956
is_a macromolecule metabolic process GO:0043170 complement activation GO:0006956
is_a response to stimulus GO:0050896 complement activation GO:0006956
regulates immune response GO:0006955 complement activation GO:0006956
positively regulates biological_process GO:0008150 complement activation GO:0006956
is_a regulation of immune response GO:0050776 complement activation GO:0006956
is_a positive regulation of immune response GO:0050778 complement activation GO:0006956
is_a protein metabolic process GO:0019538 complement activation GO:0006956
is_a single-organism process GO:0044699 complement activation GO:0006956
positively regulates immune system process GO:0002376 complement activation GO:0006956
regulates biological_process GO:0008150 complement activation GO:0006956
is_a positive regulation of response to stimulus GO:0048584 complement activation GO:0006956
is_a regulation of response to stimulus GO:0048583 complement activation GO:0006956
positively regulates immune response GO:0006955 complement activation GO:0006956
is_a regulation of biological process GO:0050789 complement activation GO:0006956

3 Synonyms

Name Type
complement activity related_synonym
complement cascade exact_synonym
complement response exact_synonym