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GO Term : GO:0000165 MAPK cascade GO

Namespace  biological_process Obsolete  false
description  An intracellular protein kinase cascade containing at least a MAPK, a MAPKK and a MAP3K. The cascade can also contain two additional tiers: the upstream MAP4K and the downstream MAP Kinase-activated kinase (MAPKAPK). The kinases in each tier phosphorylate and activate the kinases in the downstream tier to transmit a signal within a cell.

1 Data Sets

Name URL
GO Annotation from FlyBase  

1 Ontology

Name
GO

42 Ontology Annotations


Subject . Secondary Identifier

Subject . Name

Subject . Symbol

Ontology Term . Identifier

Ontology Term . Name
CG3166 anterior open aop GO:0000165 MAPK cascade
CG5680 basket bsk GO:0000165 MAPK cascade
CG2275 Jun-related antigen Jra GO:0000165 MAPK cascade
CG12559 rolled rl GO:0000165 MAPK cascade
CG15793 Downstream of raf1 Dsor1 GO:0000165 MAPK cascade
CG4353 hemipterous hep GO:0000165 MAPK cascade
CG5475 Mpk2 Mpk2 GO:0000165 MAPK cascade
CG7717 Mekk1 Mekk1 GO:0000165 MAPK cascade
CG7393 p38b p38b GO:0000165 MAPK cascade
CG32179 Keren Krn GO:0000165 MAPK cascade
CG9491 PDZ domain-containing guanine nucleotide exchange factor PDZ-GEF GO:0000165 MAPK cascade
CG9491 PDZ domain-containing guanine nucleotide exchange factor PDZ-GEF GO:0000165 MAPK cascade
CG9491 PDZ domain-containing guanine nucleotide exchange factor PDZ-GEF GO:0000165 MAPK cascade
CG42320 Darkener of apricot Doa GO:0000165 MAPK cascade
CG42320 Darkener of apricot Doa GO:0000165 MAPK cascade
CG42320 Darkener of apricot Doa GO:0000165 MAPK cascade
CG42320 Darkener of apricot Doa GO:0000165 MAPK cascade
  dyf-5 GO:0000165 MAPK cascade
  dyf-5 GO:0000165 MAPK cascade
  dlk-1 GO:0000165 MAPK cascade
  C05D10.2 GO:0000165 MAPK cascade
  C05D10.2 GO:0000165 MAPK cascade
  C05D10.2 GO:0000165 MAPK cascade
  mpk-2 GO:0000165 MAPK cascade
  mpk-2 GO:0000165 MAPK cascade
  mpk-2 GO:0000165 MAPK cascade
  kgb-2 GO:0000165 MAPK cascade
  pkc-1 GO:0000165 MAPK cascade
  pmk-3 GO:0000165 MAPK cascade
  pmk-3 GO:0000165 MAPK cascade

22 Parents

Identifier Name
GO:0044699 single-organism process
GO:0009987 cellular process
GO:0008150 biological_process
GO:0044763 single-organism cellular process
GO:0050896 response to stimulus
GO:0051716 cellular response to stimulus
GO:0044237 cellular metabolic process
GO:0044710 single-organism metabolic process
GO:0008152 metabolic process
GO:0065007 biological regulation
GO:0050794 regulation of cellular process
GO:0050789 regulation of biological process
GO:0007154 cell communication
GO:0006793 phosphorus metabolic process
GO:0016310 phosphorylation
GO:0006796 phosphate-containing compound metabolic process
GO:0007165 signal transduction
GO:0044700 single organism signaling
GO:0023052 signaling
GO:0000165 MAPK cascade
GO:0035556 intracellular signal transduction
GO:0023014 signal transduction by phosphorylation

128 Relations

Relationship
Parent Term . Name

Parent Term . Identifier

Child Term . Name

Child Term . Identifier
is_a MAPK cascade GO:0000165 MAPK cascade involved in osmosensory signaling pathway GO:0000161
is_a intracellular signal transduction GO:0035556 MAPK cascade GO:0000165
is_a signal transduction by phosphorylation GO:0023014 MAPK cascade GO:0000165
is_a signal transduction GO:0007165 MAPK cascade GO:0000165
is_a single-organism metabolic process GO:0044710 MAPK cascade GO:0000165
is_a biological regulation GO:0065007 MAPK cascade GO:0000165
is_a cellular metabolic process GO:0044237 MAPK cascade GO:0000165
is_a single-organism process GO:0044699 MAPK cascade GO:0000165
part_of single-organism process GO:0044699 MAPK cascade GO:0000165
part_of biological_process GO:0008150 MAPK cascade GO:0000165
part_of cellular process GO:0009987 MAPK cascade GO:0000165
part_of single organism signaling GO:0044700 MAPK cascade GO:0000165
part_of signaling GO:0023052 MAPK cascade GO:0000165
is_a metabolic process GO:0008152 MAPK cascade GO:0000165
is_a regulation of biological process GO:0050789 MAPK cascade GO:0000165
is_a phosphate-containing compound metabolic process GO:0006796 MAPK cascade GO:0000165
is_a biological_process GO:0008150 MAPK cascade GO:0000165
part_of cell communication GO:0007154 MAPK cascade GO:0000165
part_of single-organism cellular process GO:0044763 MAPK cascade GO:0000165
is_a phosphorus metabolic process GO:0006793 MAPK cascade GO:0000165
is_a cellular process GO:0009987 MAPK cascade GO:0000165
is_a phosphorylation GO:0016310 MAPK cascade GO:0000165
is_a cellular response to stimulus GO:0051716 MAPK cascade GO:0000165
is_a regulation of cellular process GO:0050794 MAPK cascade GO:0000165
is_a response to stimulus GO:0050896 MAPK cascade GO:0000165
regulates cellular process GO:0009987 MAPK cascade GO:0000165
is_a single-organism cellular process GO:0044763 MAPK cascade GO:0000165
regulates biological_process GO:0008150 MAPK cascade GO:0000165
regulates MAPK cascade GO:0000165 activation of MAPKKK activity involved in osmosensory signaling pathway GO:0000167
regulates MAPK cascade GO:0000165 activation of MAPKK activity involved in osmosensory signaling pathway GO:0000168

9 Synonyms

Name Type
ERK/MAPK cascade narrow_synonym
MAPKKK cascade during sporulation narrow_synonym
MAPKKK cascade exact_synonym
mitogen-activated protein kinase cascade exact_synonym
MAP kinase kinase kinase cascade exact_synonym
MAPK signal transduction exact_synonym
MAPK signalling related_synonym
MAP kinase cascade exact_synonym
MAPK signaling related_synonym