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Protein Domain : IPR028179

Name  Tight junction-associated protein 1 Short Name  Tjap1
Type  Family Description  Tight junction-associated protein 1 (also known as Pilt) is a family of eukaryotic tight junction-proteins. Pilt is a component of TJs (Tight junctions) rather than AJs (Adhesin junctions). TJs function as a barrier preventing solutes and water from passing freely through the paracellular pathway. TJs consist of transmembrane proteins (claudin, occludin, and JAM) plus many peripheral membrane proteins and cell polarity molecules. Pilt is a novel peripheral membrane protein which is incorporated into TJs after TJ strands are formed, thereby the name Pilt for 'protein incorporated later into TJs'. Pilt binds to the guanylate-kinase region of hDlg/SAP97 (disk large homologue/synapse-associated protein 97) [].

Publication Counts Displayer

0 Child Features

0 Contains

1 Cross References

Identifier
Source . Name

Subject . Primary Identifier
PF15453 PFAM IPR028179

2 Data Sets

Name URL
InterPro data set  
InterPro GO Annotation data set  

0 Found In

1 GO Annotation


Subject . Secondary Identifier

Subject . Name

Subject . Symbol

Ontology Term . Identifier

Ontology Term . Name
Tight junction-associated protein 1   GO:0005923 tight junction

1 Ontology Annotations


Subject . Secondary Identifier

Subject . Name

Subject . Symbol

Ontology Term . Identifier

Ontology Term . Name
Tight junction-associated protein 1   GO:0005923 tight junction

0 Parent Features

0 Proteins