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Protein Domain : IPR024774

Name  Pleckstrin homology domain, Mcp5-type Short Name  PH_dom-Mcp5-type
Type  Domain Description  This pleckstrin homology domain is found in eukaryotic proteins, including Mcp5, a fungal protein that anchors dynein at the cell cortex during the horsetail phase (prophase I) of meiosis. During prophase I of fission yeast all the telomeres become bundled at the spindle pole body and subsequently the nucleus undergoes a dynamic oscillation, resulting in elongated nuclear morphology known as "horsetail" nucleus. The pleckstrin homology domain is necessary for the cortical localisation of the Mcp5 protein during meiosis [].

Publication Counts Displayer

0 Child Features

0 Contains

1 Cross References

Identifier
Source . Name

Subject . Primary Identifier
PF12814 PFAM IPR024774

2 Data Sets

Name URL
InterPro data set  
InterPro GO Annotation data set  

0 Found In

4 GO Annotation


Subject . Secondary Identifier

Subject . Name

Subject . Symbol

Ontology Term . Identifier

Ontology Term . Name
Pleckstrin homology domain, Mcp5-type   GO:0005515 protein binding
Pleckstrin homology domain, Mcp5-type   GO:0005543 phospholipid binding
Pleckstrin homology domain, Mcp5-type   GO:0032065 cortical protein anchoring
Pleckstrin homology domain, Mcp5-type   GO:0005938 cell cortex

4 Ontology Annotations


Subject . Secondary Identifier

Subject . Name

Subject . Symbol

Ontology Term . Identifier

Ontology Term . Name
Pleckstrin homology domain, Mcp5-type   GO:0005515 protein binding
Pleckstrin homology domain, Mcp5-type   GO:0005543 phospholipid binding
Pleckstrin homology domain, Mcp5-type   GO:0032065 cortical protein anchoring
Pleckstrin homology domain, Mcp5-type   GO:0005938 cell cortex

1 Parent Features

DB identifier Name Short Name Type
IPR001849 Pleckstrin homology domain Pleckstrin_homology Domain

0 Proteins