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Pathway : 103736 Signaling by Rho GTPases

Curated  false
Description: This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.


1 Data Sets

Name URL
Reactome data set  

44 Genes

DB identifier Secondary Identifier Symbol Name Source Organism
FBgn0023172 CG9635 RhoGEF2 Rho guanine nucleotide exchange factor 2 FlyBase D. melanogaster
FBgn0039140 CG5410 Miro Mitochondrial Rho FlyBase D. melanogaster
FBgn0025836 CG40494 RhoGAP1A Rho GTPase activating protein at 1A FlyBase D. melanogaster
FBgn0010341 CG12530 Cdc42 Cdc42 FlyBase D. melanogaster
FBgn0014020 CG8416 Rho1 Rho1 FlyBase D. melanogaster
FBgn0014011 CG8556 Rac2 Rac2 FlyBase D. melanogaster
FBgn0010333 CG2248 Rac1 Rac1 FlyBase D. melanogaster
FBgn0086901 CG34389 cv-c crossveinless c FlyBase D. melanogaster
FBgn0023388 CG1099 Dap160 Dynamin associated protein 160 FlyBase D. melanogaster
FBgn0035533 CG15015 Cip4 Cip4 FlyBase D. melanogaster
FBgn0024277 CG18214 trio trio FlyBase D. melanogaster
FBgn0039532 CG5588 Mtl Mig-2-like FlyBase D. melanogaster
FBgn0259216 CG42316 RhoGAP102A Rho GTPase activating protein at 102A FlyBase D. melanogaster
FBgn0050115 CG30115 GEFmeso Guanine nucleotide exchange factor in mesoderm FlyBase D. melanogaster
FBgn0262562 CG43102 CG43102 FlyBase D. melanogaster
FBgn0004868 CG4422 Gdi GDP dissociation inhibitor FlyBase D. melanogaster
FBgn0031118 CG1412 RhoGAP19D Rho GTPase activating protein at 19D FlyBase D. melanogaster
FBgn0039883 CG1976 RhoGAP100F Rho GTPase activating protein at 100F FlyBase D. melanogaster
FBgn0003041 CG8114 pbl pebble FlyBase D. melanogaster
FBgn0026375 CG32555 RhoGAPp190 Rho GTPase activating protein p190 FlyBase D. melanogaster
FBgn0036257 CG6811 RhoGAP68F Rho GTPase activating protein at 68F FlyBase D. melanogaster
FBgn0026056 CG11622 Rlip Ral interacting protein FlyBase D. melanogaster
FBgn0028494 CG6424 CG6424 FlyBase D. melanogaster
FBgn0264707 CG43976 RhoGEF3 Rho guanine nucleotide exchange factor 3 FlyBase D. melanogaster
FBgn0030808 CG4937 RhoGAP15B Rho GTPase activating protein at 15B FlyBase D. melanogaster
FBgn0086356 CG13345 tum tumbleweed FlyBase D. melanogaster
FBgn0261547 CG42665 Exn Ephexin FlyBase D. melanogaster
FBgn0032796 CG10188 CG10188 FlyBase D. melanogaster
FBgn0085447 CG34418 sif still life FlyBase D. melanogaster
FBgn0036921 CG7823 RhoGDI RhoGDI FlyBase D. melanogaster

135 Proteins

DB identifier Primary Accession
Organism . Name
FBpp0086123 A1ZAN7 Drosophila melanogaster
FBpp0086124 A1ZAN6 Drosophila melanogaster
FBpp0072614 P40792 Drosophila melanogaster
FBpp0083980 Q8IMX7 Drosophila melanogaster
FBpp0301154 P40793 Drosophila melanogaster
FBpp0080821 Q9VIV0 Drosophila melanogaster
FBpp0074665 Q9VW59 Drosophila melanogaster
FBpp0077843 Q9VPG7 Drosophila melanogaster
FBpp0081099 P40809 Drosophila melanogaster
FBpp0079458 Q9VLB7 Drosophila melanogaster
FBpp0306076 Q8IRJ3 Drosophila melanogaster
FBpp0089130 P48148 Drosophila melanogaster
FBpp0080851 Q9VIS1 Drosophila melanogaster
FBpp0083406 Q9VDG2 Drosophila melanogaster
FBpp0305023 P48554 Drosophila melanogaster
FBpp0072543 Q8IRI4 Drosophila melanogaster
FBpp0072540 Q7KVD1 Drosophila melanogaster
FBpp0089283 Q7YZA0 Drosophila melanogaster
FBpp0072541 Q8IRI5 Drosophila melanogaster
FBpp0306082 E1JHV3 Drosophila melanogaster
FBpp0306081 Q9W0S0 Drosophila melanogaster
FBpp0111544 A8JR05 Drosophila melanogaster
FBpp0111543 Q9VFK2 Drosophila melanogaster
FBpp0081031 Q9VIF7 Drosophila melanogaster
FBpp0081032 Q8INU2 Drosophila melanogaster
FBpp0070304 O46094 Drosophila melanogaster
FBpp0077012 Q9VRA6 Drosophila melanogaster
FBpp0083438 Q9VDE9 Drosophila melanogaster
FBpp0073979 Q9VXQ2 Drosophila melanogaster
FBpp0084563 Q7JWS8 Drosophila melanogaster