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Pathway : 138555 Downregulation of TGF-beta receptor signaling

Curated  false
Description: This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.


1 Data Sets

Name URL
Reactome data set  

10 Genes

DB identifier Secondary Identifier Symbol Name Source Organism
FBgn0020497 CG13387 emb embargoed FlyBase D. melanogaster
FBgn0025800 CG2262 Smox Smad on X FlyBase D. melanogaster
FBgn0020493 CG5201 Dad Daughters against dpp FlyBase D. melanogaster
FBgn0029006 CG4943 lack lethal with a checkpoint kinase FlyBase D. melanogaster
FBgn0259174 CG42279 Nedd4 Nedd4 FlyBase D. melanogaster
FBgn0003941 CG2960 RpL40 Ribosomal protein L40 FlyBase D. melanogaster
FBgn0030735 CG3632 CG3632 FlyBase D. melanogaster
FBgn0003943 CG11624 Ubi-p63E Ubiquitin-63E FlyBase D. melanogaster
FBgn0027052 CG5203 CHIP CHIP FlyBase D. melanogaster
FBgn0003942 CG5271 RpS27A Ribosomal protein S27A FlyBase D. melanogaster

19 Proteins

DB identifier Primary Accession
Organism . Name
FBpp0073035 P0CG69 Drosophila melanogaster
FBpp0099512 Q5U110 Drosophila melanogaster
FBpp0079606 P15357 Drosophila melanogaster
FBpp0079617 Q9XYW6 Drosophila melanogaster
FBpp0079278 Q9TVM2 Drosophila melanogaster
FBpp0086011 Q9V853 Drosophila melanogaster
FBpp0071140 O96660 Drosophila melanogaster
FBpp0077159 P18101 Drosophila melanogaster
FBpp0289746 Q9VVI3 Drosophila melanogaster
FBpp0111901 Q7YU03 Drosophila melanogaster
FBpp0111902 A8JV04 Drosophila melanogaster
Q8SZT4_DROME Q8SZT4 Drosophila melanogaster
O15968_DROME O15968 Drosophila melanogaster
Q9TZQ2_DROME Q9TZQ2 Drosophila melanogaster
Q86NL2_DROME Q86NL2 Drosophila melanogaster
Q86DT7 Drosophila melanogaster
Q86DT8 Drosophila melanogaster
Q86DT5 Drosophila melanogaster
Q86DT6 Drosophila melanogaster