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Pathway : 79935 Axonal growth inhibition (RHOA activation)

Curated  false
Description: This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.


1 Data Sets

Name URL
Reactome data set  

2 Genes

DB identifier Secondary Identifier Symbol Name Source Organism
FBgn0023172 CG9635 RhoGEF2 Rho guanine nucleotide exchange factor 2 FlyBase D. melanogaster
FBgn0014020 CG8416 Rho1 Rho1 FlyBase D. melanogaster

7 Proteins

DB identifier Primary Accession
Organism . Name
FBpp0086123 A1ZAN7 Drosophila melanogaster
FBpp0086124 A1ZAN6 Drosophila melanogaster
FBpp0089130 P48148 Drosophila melanogaster
Q8T9E3_DROME Q8T9E3 Drosophila melanogaster
E8NH10_DROME E8NH10 Drosophila melanogaster
O44113_DROME O44113 Drosophila melanogaster
O44381_DROME O44381 Drosophila melanogaster