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Pathway : 33936 p38MAPK events

Curated  false
Description: This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.

1 Data Sets

Name URL
Reactome data set  

6 Genes

DB identifier Secondary Identifier Symbol Name Source Organism
FBgn0024846 CG7393 p38b p38b FlyBase D. melanogaster
FBgn0015765 CG5475 Mpk2 Mpk2 FlyBase D. melanogaster
FBgn0015286 CG2849 Rala Ras-like protein A FlyBase D. melanogaster
FBgn0026376 CG8865 Rgl Ral guanine nucleotide dissociation stimulator-like ortholog (M. musculus) FlyBase D. melanogaster
FBgn0003205 CG9375 Ras85D Ras oncogene at 85D FlyBase D. melanogaster
FBgn0013987 CG3086 MAPk-Ak2 MAP kinase activated protein-kinase-2 FlyBase D. melanogaster

8 Proteins

DB identifier Primary Accession
Organism . Name
FBpp0070802 P49071 Drosophila melanogaster
FBpp0081600 P08646 Drosophila melanogaster
FBpp0070559 P48555 Drosophila melanogaster
FBpp0083965 O62618 Drosophila melanogaster
FBpp0075535 Q9U4U5 Drosophila melanogaster
FBpp0075536 Q86BI2 Drosophila melanogaster
FBpp0080111 O61443 Drosophila melanogaster
Q9GR11_DROME Q9GR11 Drosophila melanogaster