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Pathway : 34312 Activation of ATR in response to replication stress

Curated  false
Description: This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.


1 Data Sets

Name URL
Reactome data set  

33 Genes

DB identifier Secondary Identifier Symbol Name Source Organism
FBgn0261278 CG17161 grp grapes FlyBase D. melanogaster
FBgn0003525 CG1395 stg string FlyBase D. melanogaster
FBgn0002673 CG4965 twe twine FlyBase D. melanogaster
FBgn0005654 CG4088 lat latheo FlyBase D. melanogaster
FBgn0032906 CG9273 RPA2 Replication protein A2 FlyBase D. melanogaster
FBgn0030871 CG8142 CG8142 FlyBase D. melanogaster
FBgn0028360 CG32742 l(1)G0148 lethal (1) G0148 FlyBase D. melanogaster
FBgn0024332 CG4206 Mcm3 Minichromosome maintenance 3 FlyBase D. melanogaster
FBgn0032929 CG9241 Mcm10 Sensitized chromosome inheritance modifier 19 FlyBase D. melanogaster
FBgn0015270 CG3041 Orc2 Origin recognition complex subunit 2 FlyBase D. melanogaster
FBgn0015929 CG1616 dpa disc proliferation abnormal FlyBase D. melanogaster
FBgn0000307 CG5813 chif chiffon FlyBase D. melanogaster
FBgn0028700 CG6258 RfC38 Replication factor C 38kD subunit FlyBase D. melanogaster
FBgn0022772 CG10667 Orc1 Origin recognition complex subunit 1 FlyBase D. melanogaster
FBgn0020633 CG4978 Mcm7 Minichromosome maintenance 7 FlyBase D. melanogaster
FBgn0026417 CG2525 Hus1-like Hus1-like FlyBase D. melanogaster
FBgn0025807 CG3945 Rad9 Rad9 FlyBase D. melanogaster
FBgn0010173 CG9633 RpA-70 Replication Protein A 70 FlyBase D. melanogaster
FBgn0023180 CG1584 Orc6 Origin recognition complex subunit 6 FlyBase D. melanogaster
FBgn0032677 CG5790 CG5790 FlyBase D. melanogaster
FBgn0052251 CG32251 Claspin Claspin FlyBase D. melanogaster
FBgn0026778 CG3240 Rad1 Radiation insensitive 1 FlyBase D. melanogaster
FBgn0003227 CG31293 rec recombination-defective FlyBase D. melanogaster
FBgn0014861 CG7538 Mcm2 Minichromosome maintenance 2 FlyBase D. melanogaster
FBgn0026143 CG3658 CDC45L CDC45L FlyBase D. melanogaster
FBgn0015271 CG7833 Orc5 Origin recognition complex subunit 5 FlyBase D. melanogaster
FBgn0023181 CG2917 Orc4 Origin recognition complex subunit 4 FlyBase D. melanogaster
FBgn0032244 CG5313 RfC3 Replication factor C subunit 3 FlyBase D. melanogaster
FBgn0035918 CG5971 Cdc6 Cdc6 FlyBase D. melanogaster
FBgn0017577 CG4082 Mcm5 Minichromosome maintenance 5 FlyBase D. melanogaster

59 Proteins

DB identifier Primary Accession
Organism . Name
FBpp0073142 Q8IRB5 Drosophila melanogaster
FBpp0070911 Q9W3Y1 Drosophila melanogaster
FBpp0079812 Q9U9Q1 Drosophila melanogaster
FBpp0080412 Q03019 Drosophila melanogaster
FBpp0081756 Q9VGW6 Drosophila melanogaster
FBpp0088033 O16810 Drosophila melanogaster
FBpp0072330 Q9W102 Drosophila melanogaster
FBpp0080120 Q24169 Drosophila melanogaster
FBpp0082433 O96532 Drosophila melanogaster
FBpp0087566 Q9Y1B2 Drosophila melanogaster
FBpp0081356 Q24492 Drosophila melanogaster
FBpp0086881 Q7K2L1 Drosophila melanogaster
FBpp0081317 P49735 Drosophila melanogaster
FBpp0080603 Q9VJ90 Drosophila melanogaster
FBpp0070913 Q9V461 Drosophila melanogaster
FBpp0082647 Q9VF30 Drosophila melanogaster
FBpp0078516 Q9VN60 Drosophila melanogaster
FBpp0074847 O96533 Drosophila melanogaster
FBpp0084766 P20483 Drosophila melanogaster
FBpp0081004 Q9VIE6 Drosophila melanogaster
FBpp0080443 O61661 Drosophila melanogaster
FBpp0079609 Q9VKW3 Drosophila melanogaster
FBpp0077427 Q9VQD4 Drosophila melanogaster
FBpp0076312 Q9XYU0 Drosophila melanogaster
FBpp0074246 Q9VX15 Drosophila melanogaster
FBpp0070729 Q9XYU1 Drosophila melanogaster
FBpp0088055 Q26454 Drosophila melanogaster
FBpp0082329 Q24168 Drosophila melanogaster
FBpp0080967 Q9VIH1 Drosophila melanogaster
FBpp0080396 Q9NK54 Drosophila melanogaster