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Pathway : 118381 Disease

Curated  false
Description: This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.


1 Data Sets

Name URL
Reactome data set  

326 Genes

DB identifier Secondary Identifier Symbol Name Source Organism
FBgn0031871 CG10158 CG10158 FlyBase D. melanogaster
FBgn0015806 CG10539 S6k RPS6-p70-protein kinase FlyBase D. melanogaster
FBgn0030512 CG9940 CG9940 FlyBase D. melanogaster
FBgn0260745 CG3359 mfas midline fasciclin FlyBase D. melanogaster
FBgn0028704 CG18660 Nckx30C Nckx30C FlyBase D. melanogaster
FBgn0016917 CG4257 Stat92E Signal-transducer and activator of transcription protein at 92E FlyBase D. melanogaster
FBgn0000317 CG7595 ck crinkled FlyBase D. melanogaster
FBgn0020388 CG4107 Gcn5 Gcn5 ortholog FlyBase D. melanogaster
FBgn0261617 CG15319 nej nejire FlyBase D. melanogaster
FBgn0003731 CG10079 Egfr Epidermal growth factor receptor FlyBase D. melanogaster
FBgn0025836 CG40494 RhoGAP1A Rho GTPase activating protein at 1A FlyBase D. melanogaster
FBgn0005632 CG1945 faf fat facets FlyBase D. melanogaster
FBgn0000382 CG3954 csw corkscrew FlyBase D. melanogaster
FBgn0003371 CG2621 sgg shaggy FlyBase D. melanogaster
FBgn0000463 CG3619 Dl Delta FlyBase D. melanogaster
FBgn0032749 CG10493 Phlpp PH domain leucine-rich repeat protein phosphatase FlyBase D. melanogaster
FBgn0038755 CG4451 Hs6st Heparan sulfate 6-O-sulfotransferase FlyBase D. melanogaster
FBgn0011676 CG6713 Nos Nitric oxide synthase FlyBase D. melanogaster
FBgn0034970 CG4005 yki yorkie FlyBase D. melanogaster
FBgn0004647 CG3936 N Notch FlyBase D. melanogaster
FBgn0016984 CG9985 sktl skittles FlyBase D. melanogaster
FBgn0028582 CG8532 lqf liquid facets FlyBase D. melanogaster
FBgn0263930 CG4974 dally division abnormally delayed FlyBase D. melanogaster
FBgn0027621 CG3400 Pfrx 6-phosphofructo-2-kinase FlyBase D. melanogaster
FBgn0014388 CG1921 sty sprouty FlyBase D. melanogaster
FBgn0263598 CG3762 Vha68-2 Vacuolar H[+] ATPase 68 kDa subunit 2 FlyBase D. melanogaster
FBgn0011573 CG12019 Cdc37 Cdc37 FlyBase D. melanogaster
FBgn0032054 CG13090 CG13090 FlyBase D. melanogaster
FBgn0026379 CG5671 Pten Pten FlyBase D. melanogaster
FBgn0040508 CG5983 ACXC ACXC FlyBase D. melanogaster

685 Proteins

DB identifier Primary Accession
Organism . Name
FBpp0076820 Q94533 Drosophila melanogaster
FBpp0073676 Q9VYA0 Drosophila melanogaster
FBpp0080693 Q9VJ07 Drosophila melanogaster
FBpp0076349 Q9VSL3 Drosophila melanogaster
FBpp0079777 Q27571 Drosophila melanogaster
FBpp0074487 Q0KHQ6 Drosophila melanogaster
FBpp0074486 Q9VWH7 Drosophila melanogaster
FBpp0073004 O44783 Drosophila melanogaster
FBpp0070612 O97422 Drosophila melanogaster
FBpp0079295 Q9VLJ8 Drosophila melanogaster
FBpp0075822 Q9VTI6 Drosophila melanogaster
FBpp0099930 Q2PDU2 Drosophila melanogaster
FBpp0079994 Q9VK53 Drosophila melanogaster
FBpp0099953 Q9Y169 Drosophila melanogaster
FBpp0099492 Q9VXU0 Drosophila melanogaster
FBpp0087053 A1Z916 Drosophila melanogaster
FBpp0087054 Q7JR08 Drosophila melanogaster
FBpp0073880 Q7KUZ9 Drosophila melanogaster
FBpp0082288 Q9VFS2 Drosophila melanogaster
FBpp0079790 Q9VKJ0 Drosophila melanogaster
FBpp0079874 Q9VKD3 Drosophila melanogaster
FBpp0085560 A1ZBX7 Drosophila melanogaster
FBpp0072526 P37159 Drosophila melanogaster
FBpp0085583 Q7JR83 Drosophila melanogaster
FBpp0086833 Q5BIL9 Drosophila melanogaster
FBpp0073488 Q9VYL1 Drosophila melanogaster
FBpp0086624 Q9V730 Drosophila melanogaster
FBpp0290537 Q8IRF5 Drosophila melanogaster
FBpp0081966 Q9VGE9 Drosophila melanogaster
FBpp0081964 Q9VGF0 Drosophila melanogaster