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Pathway : 87930 Inactivation of Cdc42 and Rac

Curated  false
Description: This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.


1 Data Sets

Name URL
Reactome data set  

8 Genes

DB identifier Secondary Identifier Symbol Name Source Organism
FBgn0041097 CG5423 robo3 robo3 FlyBase D. melanogaster
FBgn0002543 CG5481 lea leak FlyBase D. melanogaster
FBgn0010341 CG12530 Cdc42 Cdc42 FlyBase D. melanogaster
FBgn0010333 CG2248 Rac1 Rac1 FlyBase D. melanogaster
FBgn0264089 CG43758 sli slit FlyBase D. melanogaster
FBgn0041604 CG32146 dlp dally-like FlyBase D. melanogaster
FBgn0005631 CG13521 robo roundabout FlyBase D. melanogaster
FBgn0038853 CG3421 RhoGAP93B Rho GTPase activating protein at 93B FlyBase D. melanogaster

18 Proteins

DB identifier Primary Accession
Organism . Name
FBpp0072614 P40792 Drosophila melanogaster
FBpp0301154 P40793 Drosophila melanogaster
FBpp0071833 Q7KVK3 Drosophila melanogaster
FBpp0083438 Q9VDE9 Drosophila melanogaster
FBpp0077606 Q9VQ08 Drosophila melanogaster
FBpp0075431 Q9VUG1 Drosophila melanogaster
FBpp0077587 Q9VPZ7 Drosophila melanogaster
FBpp0303575 P24014 Drosophila melanogaster
O44924_DROME O44924 Drosophila melanogaster
Q9W213_DROME Q9W213 Drosophila melanogaster
Q9GPP6_DROME Q9GPP6 Drosophila melanogaster
Q5U176_DROME Q5U176 Drosophila melanogaster
Q9GPL5_DROME Q9GPL5 Drosophila melanogaster
Q9VQ07_DROME Q9VQ07 Drosophila melanogaster
Q9GPP7_DROME Q9GPP7 Drosophila melanogaster
C0PTX4 Drosophila melanogaster
Q058V6 Drosophila melanogaster
C4IXX6 Drosophila melanogaster