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Pathway : 162275 Constitutive Signaling by NOTCH1 HD Domain Mutants

Curated  false
Description: This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.

1 Data Sets

Name URL
Reactome data set  

8 Genes

DB identifier Secondary Identifier Symbol Name Source Organism
FBgn0000463 CG3619 Dl Delta FlyBase D. melanogaster
FBgn0004647 CG3936 N Notch FlyBase D. melanogaster
FBgn0263601 CG5841 mib1 mind bomb 1 FlyBase D. melanogaster
FBgn0259984 CG7147 kuz kuzbanian FlyBase D. melanogaster
FBgn0004197 CG6127 Ser Serrate FlyBase D. melanogaster
FBgn0003941 CG2960 RpL40 Ribosomal protein L40 FlyBase D. melanogaster
FBgn0003943 CG11624 Ubi-p63E Ubiquitin-63E FlyBase D. melanogaster
FBgn0003942 CG5271 RpS27A Ribosomal protein S27A FlyBase D. melanogaster

13 Proteins

DB identifier Primary Accession
Organism . Name
FBpp0075275 Q9VUX2 Drosophila melanogaster
FBpp0073035 P0CG69 Drosophila melanogaster
FBpp0100122 Q59DZ3 Drosophila melanogaster
FBpp0083153 P10041 Drosophila melanogaster
FBpp0070483 P07207 Drosophila melanogaster
FBpp0079606 P15357 Drosophila melanogaster
FBpp0080087 Q9VJW9 Drosophila melanogaster
FBpp0077159 P18101 Drosophila melanogaster
FBpp0309702 A8DZ03 Drosophila melanogaster
FBpp0290626 A8DZ02 Drosophila melanogaster
SERR_DROME P18168 Drosophila melanogaster
Q7YU78_DROME Q7YU78 Drosophila melanogaster
Q94902_DROME Q94902 Drosophila melanogaster