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Pathway : 139259 JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1

Curated  false
Description: This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.

1 Data Sets

Name URL
Reactome data set  

11 Genes

DB identifier Secondary Identifier Symbol Name Source Organism
FBgn0010303 CG4353 hep hemipterous FlyBase D. melanogaster
FBgn0000229 CG5680 bsk basket FlyBase D. melanogaster
FBgn0024326 CG9738 Mkk4 MAP kinase kinase 4 FlyBase D. melanogaster
FBgn0001297 CG33956 kay kayak FlyBase D. melanogaster
FBgn0265464 CG10961 Traf6 TNF-receptor-associated factor 6 FlyBase D. melanogaster
FBgn0010441 CG5974 pll pelle FlyBase D. melanogaster
FBgn0001291 CG2275 Jra Jun-related antigen FlyBase D. melanogaster
FBgn0024222 CG4201 ird5 immune response deficient 5 FlyBase D. melanogaster
FBgn0086358 CG7417 Tab2 TAK1-associated binding protein 2 FlyBase D. melanogaster
FBgn0026323 CG18492 Tak1 TGF-beta activated kinase 1 FlyBase D. melanogaster
FBgn0041205 CG16910 key kenny FlyBase D. melanogaster

18 Proteins

DB identifier Primary Accession
Organism . Name
FBpp0073578 Q23977 Drosophila melanogaster
FBpp0085704 Q6NQZ7 Drosophila melanogaster
FBpp0099941 A8MPH9 Drosophila melanogaster
FBpp0079676 P92208 Drosophila melanogaster
FBpp0081378 O61444 Drosophila melanogaster
FBpp0077011 Q9V3Q6 Drosophila melanogaster
FBpp0087499 P18289 Drosophila melanogaster
FBpp0084549 Q05652 Drosophila melanogaster
FBpp0288515 P21525 Drosophila melanogaster
FBpp0071136 Q9W3I9 Drosophila melanogaster
IKKB_DROME Q9VEZ5 Drosophila melanogaster
NEMO_DROME Q9GYV5 Drosophila melanogaster
Q9UAC4_DROME Q9UAC4 Drosophila melanogaster
Q9XYQ9_DROME Q9XYQ9 Drosophila melanogaster
Q7KPX5_DROME Q7KPX5 Drosophila melanogaster
Q7KPK6_DROME Q7KPK6 Drosophila melanogaster
Q4TZQ4_DROME Q4TZQ4 Drosophila melanogaster
Q9NFL3_DROME Q9NFL3 Drosophila melanogaster