| Curated | false |
| Description: | Reviewed: Tatar, M, 2004-05-12 07:00:00The insulin/IGF-like signaling (IIS) and TOR pathways are responsible for conveying nutrient signals and regulating growth in Drosophila. Activation of the IIS pathway occurs when insulin-like peptides bind the insulin receptor. Activation of the TOR signaling pathway occurs in the presence of amino acids via an unknown mechanism. Together, these pathways coordinate cell-autonomous and non cell-autonomous growth responses to nutrients. The exact way these two signaling pathways are coordinated and their outputs balanced are not understood.Authored: Broughton, S, Gianakou, M, Leevers, SJ, Partridge, L, Piper, M, Jassal, B, 2005-06-14 11:07:15 |
