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Pathway : 88314 Heme biosynthesis

Curated  false
Description: This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.


1 Data Sets

Name URL
Reactome data set  

11 Genes

DB identifier Secondary Identifier Symbol Name Source Organism
FBgn0033428 CG1818 Updo Updo FlyBase D. melanogaster
FBgn0034938 CG3803 CG3803 FlyBase D. melanogaster
FBgn0020764 CG3017 Alas Aminolevulinate synthase FlyBase D. melanogaster
FBgn0010786 CG9165 l(3)02640 lethal (3) 02640 FlyBase D. melanogaster
FBgn0266268 CG2098 FeCH Ferrochelatase FlyBase D. melanogaster
FBgn0021944 CG3433 Coprox Coproporphyrinogen oxidase FlyBase D. melanogaster
FBgn0036271 CG10335 Pbgs Porphobilinogen synthase FlyBase D. melanogaster
FBgn0032222 CG5037 CG5037 FlyBase D. melanogaster
FBgn0020018 CG5796 Ppox Protoporphyrinogen oxidase FlyBase D. melanogaster
FBgn0038361 CG9589 CG9589 FlyBase D. melanogaster
FBgn0030066 CG1885 CG1885 FlyBase D. melanogaster

18 Proteins

DB identifier Primary Accession
Organism . Name
FBpp0087607 Q9V595 Drosophila melanogaster
FBpp0075743 Q9VTV9 Drosophila melanogaster
FBpp0078980 Q9V3D2 Drosophila melanogaster
FBpp0071211 Q9W3B3 Drosophila melanogaster
FBpp0079582 Q9VKZ1 Drosophila melanogaster
FBpp0084044 Q9VC52 Drosophila melanogaster
FBpp0072572 Q9W0G4 Drosophila melanogaster
FBpp0072117 Q9W1F5 Drosophila melanogaster
FBpp0082627 Q9VF38 Drosophila melanogaster
FBpp0072060 O18680 Drosophila melanogaster
HEMH_DROME Q9V9S8 Drosophila melanogaster
Q8T4G6_DROME Q8T4G6 Drosophila melanogaster
Q8MZD2_DROME Q8MZD2 Drosophila melanogaster
Q8T0V4_DROME Q8T0V4 Drosophila melanogaster
Q8IH53_DROME Q8IH53 Drosophila melanogaster
Q9U8D0_DROME Q9U8D0 Drosophila melanogaster
A9YK77 Drosophila melanogaster
A9YK67 Drosophila melanogaster