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Pathway : 114684 CD28 dependent PI3K/Akt signaling

Curated  false
Description: This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.

1 Data Sets

Name URL
Reactome data set  

10 Genes

DB identifier Secondary Identifier Symbol Name Source Organism
FBgn0003371 CG2621 sgg shaggy FlyBase D. melanogaster
FBgn0010379 CG4006 Akt1 Akt1 FlyBase D. melanogaster
FBgn0005198 CG6975 gig gigas FlyBase D. melanogaster
FBgn0031006 CG8002 rictor rapamycin-insensitive companion of Tor FlyBase D. melanogaster
FBgn0033935 CG10105 Sin1 SAPK-interacting protein 1 FlyBase D. melanogaster
FBgn0028978 CG5408 trbl tribbles FlyBase D. melanogaster
FBgn0020386 CG1210 Pdk1 Phosphoinositide-dependent kinase 1 FlyBase D. melanogaster
FBgn0264691 CG3004 Lst8 FlyBase D. melanogaster
FBgn0021796 CG5092 Tor Target of rapamycin FlyBase D. melanogaster
FBgn0024222 CG4201 ird5 immune response deficient 5 FlyBase D. melanogaster

17 Proteins

DB identifier Primary Accession
Organism . Name
FBpp0080003 Q9VK45 Drosophila melanogaster
FBpp0074458 Q9VWJ6 Drosophila melanogaster
FBpp0082682 Q8INB9 Drosophila melanogaster
FBpp0072366 Q9W0V1 Drosophila melanogaster
FBpp0070449 P18431 Drosophila melanogaster
FBpp0077893 Q9V3Z1 Drosophila melanogaster
FBpp0074588 Q9VW83 Drosophila melanogaster
FBpp0086616 Q9V719 Drosophila melanogaster
FBpp0071303 Q9W328 Drosophila melanogaster
IKKB_DROME Q9VEZ5 Drosophila melanogaster
Q7YU91_DROME Q7YU91 Drosophila melanogaster
Q9U9B0_DROME Q9U9B0 Drosophila melanogaster
Q7K0T0 Drosophila melanogaster
H1ZYC9 Drosophila melanogaster
H1ZYC5 Drosophila melanogaster
H1ZYD2 Drosophila melanogaster
H1ZYD3 Drosophila melanogaster