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Pathway : 77110 CTLA4 inhibitory signaling

Curated  false
Description: This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.


1 Data Sets

Name URL
Reactome data set  

6 Genes

DB identifier Secondary Identifier Symbol Name Source Organism
FBgn0027492 CG5643 wdb widerborst FlyBase D. melanogaster
FBgn0010379 CG4006 Akt1 Akt1 FlyBase D. melanogaster
FBgn0020386 CG1210 Pdk1 Phosphoinositide-dependent kinase 1 FlyBase D. melanogaster
FBgn0004177 CG7109 mts microtubule star FlyBase D. melanogaster
FBgn0042693 CG7913 PP2A-B' PP2A-B' FlyBase D. melanogaster
FBgn0260439 CG17291 Pp2A-29B Protein phosphatase 2A at 29B FlyBase D. melanogaster

15 Proteins

DB identifier Primary Accession
Organism . Name
FBpp0082977 Q9VEC6 Drosophila melanogaster
FBpp0082975 Q0KI58 Drosophila melanogaster
FBpp0082976 Q8IN90 Drosophila melanogaster
FBpp0082978 Q8IN89 Drosophila melanogaster
FBpp0082682 Q8INB9 Drosophila melanogaster
FBpp0099974 P36179 Drosophila melanogaster
FBpp0079148 P23696 Drosophila melanogaster
FBpp0072366 Q9W0V1 Drosophila melanogaster
FBpp0084573 Q9VB23 Drosophila melanogaster
FBpp0288758 Q5BIJ2 Drosophila melanogaster
FBpp0288759 B7Z0L6 Drosophila melanogaster
FBpp0288760 B7Z0L7 Drosophila melanogaster
D2NUL2_DROME D2NUL2 Drosophila melanogaster
Q9NFM7_DROME Q9NFM7 Drosophila melanogaster
C6SV32 Drosophila melanogaster