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Pathway : 81368 Signaling by GPCR

Curated  false
Description: This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.


1 Data Sets

Name URL
Reactome data set  

111 Genes

DB identifier Secondary Identifier Symbol Name Source Organism
FBgn0263116 CG15113 5-HT1B 5-hydroxytryptamine (serotonin) receptor 1B FlyBase D. melanogaster
FBgn0023172 CG9635 RhoGEF2 Rho guanine nucleotide exchange factor 2 FlyBase D. melanogaster
FBgn0004168 CG16720 5-HT1A 5-hydroxytryptamine (serotonin) receptor 1A FlyBase D. melanogaster
FBgn0039140 CG5410 Miro Mitochondrial Rho FlyBase D. melanogaster
FBgn0025836 CG40494 RhoGAP1A Rho GTPase activating protein at 1A FlyBase D. melanogaster
FBgn0004573 CG12073 5-HT7 5-hydroxytryptamine (serotonin) receptor 7 FlyBase D. melanogaster
FBgn0004009 CG4889 wg wingless FlyBase D. melanogaster
FBgn0027621 CG3400 Pfrx 6-phosphofructo-2-kinase FlyBase D. melanogaster
FBgn0040508 CG5983 ACXC ACXC FlyBase D. melanogaster
FBgn0010341 CG12530 Cdc42 Cdc42 FlyBase D. melanogaster
FBgn0050054 CG30054 CG30054 FlyBase D. melanogaster
FBgn0033756 CG17760 CG17760 FlyBase D. melanogaster
FBgn0014020 CG8416 Rho1 Rho1 FlyBase D. melanogaster
FBgn0014011 CG8556 Rac2 Rac2 FlyBase D. melanogaster
FBgn0010333 CG2248 Rac1 Rac1 FlyBase D. melanogaster
FBgn0010379 CG4006 Akt1 Akt1 FlyBase D. melanogaster
FBgn0000479 CG32498 dnc dunce FlyBase D. melanogaster
FBgn0002940 CG4550 ninaE neither inactivation nor afterpotential E FlyBase D. melanogaster
FBgn0027575 CG6706 GABA-B-R2 metabotropic GABA-B receptor subtype 2 FlyBase D. melanogaster
FBgn0023388 CG1099 Dap160 Dynamin associated protein 160 FlyBase D. melanogaster
FBgn0264815 CG44007 Pde1c FlyBase D. melanogaster
FBgn0003444 CG11561 smo smoothened FlyBase D. melanogaster
FBgn0001123 CG2835 Galphas G protein alpha s subunit FlyBase D. melanogaster
FBgn0003256 CG12559 rl rolled FlyBase D. melanogaster
FBgn0032940 CG18362 Mio Mlx interactor FlyBase D. melanogaster
FBgn0261549 CG42667 rdgA retinal degeneration A FlyBase D. melanogaster
FBgn0259243 CG42341 Pka-R1 cAMP-dependent protein kinase R1 FlyBase D. melanogaster
FBgn0004106 CG5363 cdc2 cdc2 FlyBase D. melanogaster
FBgn0261811 CG11940 pico pico FlyBase D. melanogaster
FBgn0004907 CG17870 14-3-3zeta 14-3-3zeta FlyBase D. melanogaster

264 Proteins

DB identifier Primary Accession
Organism . Name
FBpp0086123 A1ZAN7 Drosophila melanogaster
FBpp0086124 A1ZAN6 Drosophila melanogaster
FBpp0074487 Q0KHQ6 Drosophila melanogaster
FBpp0074486 Q9VWH7 Drosophila melanogaster
FBpp0099980 Q4LBB9 Drosophila melanogaster
FBpp0099930 Q2PDU2 Drosophila melanogaster
FBpp0079994 Q9VK53 Drosophila melanogaster
FBpp0099492 Q9VXU0 Drosophila melanogaster
FBpp0072614 P40792 Drosophila melanogaster
FBpp0083566 Q9Y133 Drosophila melanogaster
FBpp0083565 Q8IN24 Drosophila melanogaster
FBpp0085583 Q7JR83 Drosophila melanogaster
FBpp0087360 P16378 Drosophila melanogaster
FBpp0290537 Q8IRF5 Drosophila melanogaster
FBpp0083653 Q9VCZ3 Drosophila melanogaster
FBpp0087523 P81900 Drosophila melanogaster
FBpp0083980 Q8IMX7 Drosophila melanogaster
FBpp0082682 Q8INB9 Drosophila melanogaster
FBpp0086196 P13677 Drosophila melanogaster
FBpp0099540 P29310 Drosophila melanogaster
FBpp0099729 Q95RI9 Drosophila melanogaster
FBpp0099941 A8MPH9 Drosophila melanogaster
FBpp0099728 Q8INK3 Drosophila melanogaster
FBpp0099726 Q9VGM2 Drosophila melanogaster
FBpp0099725 Q8INK2 Drosophila melanogaster
FBpp0301154 P40793 Drosophila melanogaster
FBpp0300511 P41596 Drosophila melanogaster
FBpp0072275 P16395 Drosophila melanogaster
FBpp0086197 P05130 Drosophila melanogaster
FBpp0088443 P18502 Drosophila melanogaster