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Pathway : 98776 G beta:gamma signalling through PI3Kgamma

Curated  false
Description: This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.

1 Data Sets

Name URL
Reactome data set  

4 Genes

DB identifier Secondary Identifier Symbol Name Source Organism
FBgn0014020 CG8416 Rho1 Rho1 FlyBase D. melanogaster
FBgn0010379 CG4006 Akt1 Akt1 FlyBase D. melanogaster
FBgn0020386 CG1210 Pdk1 Phosphoinositide-dependent kinase 1 FlyBase D. melanogaster
FBgn0261854 CG42783 aPKC atypical protein kinase C FlyBase D. melanogaster

12 Proteins

DB identifier Primary Accession
Organism . Name
FBpp0082682 Q8INB9 Drosophila melanogaster
FBpp0089130 P48148 Drosophila melanogaster
FBpp0072366 Q9W0V1 Drosophila melanogaster
FBpp0292487 A1Z9X0 Drosophila melanogaster
FBpp0292490 Q0E971 Drosophila melanogaster
FBpp0292486 Q0E972 Drosophila melanogaster
FBpp0292488 Q0E974 Drosophila melanogaster
FBpp0292489 Q0E973 Drosophila melanogaster
Q9GSZ3_DROME Q9GSZ3 Drosophila melanogaster
A1Z9X1_DROME A1Z9X1 Drosophila melanogaster
Q8MT38_DROME Q8MT38 Drosophila melanogaster
D3DMT3 Drosophila melanogaster