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Pathway : 85514 GPCR downstream signaling

Curated  false
Description: This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.


1 Data Sets

Name URL
Reactome data set  

76 Genes

DB identifier Secondary Identifier Symbol Name Source Organism
FBgn0023172 CG9635 RhoGEF2 Rho guanine nucleotide exchange factor 2 FlyBase D. melanogaster
FBgn0039140 CG5410 Miro Mitochondrial Rho FlyBase D. melanogaster
FBgn0025836 CG40494 RhoGAP1A Rho GTPase activating protein at 1A FlyBase D. melanogaster
FBgn0027621 CG3400 Pfrx 6-phosphofructo-2-kinase FlyBase D. melanogaster
FBgn0040508 CG5983 ACXC ACXC FlyBase D. melanogaster
FBgn0010341 CG12530 Cdc42 Cdc42 FlyBase D. melanogaster
FBgn0050054 CG30054 CG30054 FlyBase D. melanogaster
FBgn0033756 CG17760 CG17760 FlyBase D. melanogaster
FBgn0014020 CG8416 Rho1 Rho1 FlyBase D. melanogaster
FBgn0014011 CG8556 Rac2 Rac2 FlyBase D. melanogaster
FBgn0010333 CG2248 Rac1 Rac1 FlyBase D. melanogaster
FBgn0010379 CG4006 Akt1 Akt1 FlyBase D. melanogaster
FBgn0000479 CG32498 dnc dunce FlyBase D. melanogaster
FBgn0023388 CG1099 Dap160 Dynamin associated protein 160 FlyBase D. melanogaster
FBgn0264815 CG44007 Pde1c FlyBase D. melanogaster
FBgn0001123 CG2835 Galphas G protein alpha s subunit FlyBase D. melanogaster
FBgn0032940 CG18362 Mio Mlx interactor FlyBase D. melanogaster
FBgn0261549 CG42667 rdgA retinal degeneration A FlyBase D. melanogaster
FBgn0259243 CG42341 Pka-R1 cAMP-dependent protein kinase R1 FlyBase D. melanogaster
FBgn0261811 CG11940 pico pico FlyBase D. melanogaster
FBgn0024277 CG18214 trio trio FlyBase D. melanogaster
FBgn0260442 CG6831 rhea rhea FlyBase D. melanogaster
FBgn0039532 CG5588 Mtl Mig-2-like FlyBase D. melanogaster
FBgn0004852 CG7978 Ac76E Adenylyl cyclase 76E FlyBase D. melanogaster
FBgn0050115 CG30115 GEFmeso Guanine nucleotide exchange factor in mesoderm FlyBase D. melanogaster
FBgn0262562 CG43102 CG43102 FlyBase D. melanogaster
FBgn0020386 CG1210 Pdk1 Phosphoinositide-dependent kinase 1 FlyBase D. melanogaster
FBgn0000273 CG4379 Pka-C1 cAMP-dependent protein kinase 1 FlyBase D. melanogaster
FBgn0003041 CG8114 pbl pebble FlyBase D. melanogaster
FBgn0266377 CG45019 Pde8 Phosphodiesterase 8 FlyBase D. melanogaster

220 Proteins

DB identifier Primary Accession
Organism . Name
FBpp0086123 A1ZAN7 Drosophila melanogaster
FBpp0086124 A1ZAN6 Drosophila melanogaster
FBpp0074487 Q0KHQ6 Drosophila melanogaster
FBpp0074486 Q9VWH7 Drosophila melanogaster
FBpp0099930 Q2PDU2 Drosophila melanogaster
FBpp0079994 Q9VK53 Drosophila melanogaster
FBpp0099492 Q9VXU0 Drosophila melanogaster
FBpp0072614 P40792 Drosophila melanogaster
FBpp0085583 Q7JR83 Drosophila melanogaster
FBpp0290537 Q8IRF5 Drosophila melanogaster
FBpp0087523 P81900 Drosophila melanogaster
FBpp0083980 Q8IMX7 Drosophila melanogaster
FBpp0082682 Q8INB9 Drosophila melanogaster
FBpp0086196 P13677 Drosophila melanogaster
FBpp0099729 Q95RI9 Drosophila melanogaster
FBpp0099728 Q8INK3 Drosophila melanogaster
FBpp0099726 Q9VGM2 Drosophila melanogaster
FBpp0099725 Q8INK2 Drosophila melanogaster
FBpp0301154 P40793 Drosophila melanogaster
FBpp0086197 P05130 Drosophila melanogaster
FBpp0080821 Q9VIV0 Drosophila melanogaster
FBpp0074574 Q8IQW0 Drosophila melanogaster
FBpp0085149 P32866 Drosophila melanogaster
FBpp0077843 Q9VPG7 Drosophila melanogaster
FBpp0070619 P13217 Drosophila melanogaster
FBpp0073809 P32870 Drosophila melanogaster
FBpp0070385 P11346 Drosophila melanogaster
FBpp0074573 Q9VWB7 Drosophila melanogaster
FBpp0306076 Q8IRJ3 Drosophila melanogaster
FBpp0083885 Q9VCF2 Drosophila melanogaster