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Pathway : 125904 Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha

Curated  false
Description: This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.

1 Data Sets

Name URL
Reactome data set  

11 Genes

DB identifier Secondary Identifier Symbol Name Source Organism
FBgn0023211 CG9291 Elongin-C Elongin C FlyBase D. melanogaster
FBgn0041174 CG13221 Vhl von Hippel-Lindau FlyBase D. melanogaster
FBgn0032956 CG1512 Cul-2 Cullin-2 FlyBase D. melanogaster
FBgn0266411 CG45051 sima similar FlyBase D. melanogaster
FBgn0025638 CG16982 Roc1a Roc1a FlyBase D. melanogaster
FBgn0003941 CG2960 RpL40 Ribosomal protein L40 FlyBase D. melanogaster
FBgn0011217 CG7425 eff effete FlyBase D. melanogaster
FBgn0264785 CG44015 Hph HIF prolyl hydroxylase FlyBase D. melanogaster
FBgn0003943 CG11624 Ubi-p63E Ubiquitin-63E FlyBase D. melanogaster
FBgn0023212 CG4204 Elongin-B Elongin B FlyBase D. melanogaster
FBgn0003942 CG5271 RpS27A Ribosomal protein S27A FlyBase D. melanogaster

14 Proteins

DB identifier Primary Accession
Organism . Name
FBpp0073035 P0CG69 Drosophila melanogaster
FBpp0079606 P15357 Drosophila melanogaster
FBpp0085725 Q7JWD6 Drosophila melanogaster
FBpp0087216 Q9V3C1 Drosophila melanogaster
FBpp0082477 P25867 Drosophila melanogaster
FBpp0083354 O44226 Drosophila melanogaster
FBpp0077159 P18101 Drosophila melanogaster
FBpp0085255 Q9V9R2 Drosophila melanogaster
FBpp0070117 Q9W5E1 Drosophila melanogaster
FBpp0306391 Q8SX21 Drosophila melanogaster
FBpp0306389 Q8I0C2 Drosophila melanogaster
FBpp0306390 Q9VN98 Drosophila melanogaster
FBpp0310747 Q24167 Drosophila melanogaster
Q7KYI0 Drosophila melanogaster