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Pathway : 86175 Nonhomologous End-joining (NHEJ)

Curated  false
Description: This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.


1 Data Sets

Name URL
Reactome data set  

2 Genes

DB identifier Secondary Identifier Symbol Name Source Organism
FBgn0011774 CG5247 Irbp Inverted repeat-binding protein FlyBase D. melanogaster
FBgn0041627 CG18801 Ku80 Ku80 FlyBase D. melanogaster

17 Proteins

DB identifier Primary Accession
Organism . Name
FBpp0081861 Q23976 Drosophila melanogaster
FBpp0080322 Q9I7M8 Drosophila melanogaster
Q8MSM8_DROME Q8MSM8 Drosophila melanogaster
Q9NGX6_DROME Q9NGX6 Drosophila melanogaster
B6UVX5 Drosophila melanogaster
B6UVX4 Drosophila melanogaster
B6UVX3 Drosophila melanogaster
B6UVX9 Drosophila melanogaster
B6UVX8 Drosophila melanogaster
B6UVX7 Drosophila melanogaster
B6UVW8 Drosophila melanogaster
B6UVY4 Drosophila melanogaster
B6UVY5 Drosophila melanogaster
B6UVY6 Drosophila melanogaster
B6UVY1 Drosophila melanogaster
B6UVY0 Drosophila melanogaster
B6UVY3 Drosophila melanogaster