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Pathway : 33447 Regulation of Insulin Secretion by Glucagon-like Peptide-1

Curated  false
Description: This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping in Ensembl Compara. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on the Ensembl Compara system see also: Gene orthology/paralogy prediction method.

1 Data Sets

Name URL
Reactome data set  

9 Genes

DB identifier Secondary Identifier Symbol Name Source Organism
FBgn0001123 CG2835 Galphas G protein alpha s subunit FlyBase D. melanogaster
FBgn0262593 CG43128 Shab Shaker cognate b FlyBase D. melanogaster
FBgn0000273 CG4379 Pka-C1 cAMP-dependent protein kinase 1 FlyBase D. melanogaster
FBgn0024150 CG10564 Ac78C Adenylyl cyclase 78C FlyBase D. melanogaster
FBgn0003386 CG2822 Shaw Shaker cognate w FlyBase D. melanogaster
FBgn0004636 CG1956 R Roughened FlyBase D. melanogaster
FBgn0085421 CG34392 Epac Exchange protein directly activated by cAMP ortholog (H. sapiens) FlyBase D. melanogaster
FBgn0085395 CG34366 Shawl Shaw-like FlyBase D. melanogaster
FBgn0263131 CG43373 CG43373 FlyBase D. melanogaster

14 Proteins

DB identifier Primary Accession
Organism . Name
FBpp0079448 P12370 Drosophila melanogaster
FBpp0088331 P17972 Drosophila melanogaster
FBpp0300390 A8DYR5 Drosophila melanogaster
FBpp0072746 P08645 Drosophila melanogaster
FBpp0072052 P20354 Drosophila melanogaster
FBpp0111548 Q7K3Z6 Drosophila melanogaster
FBpp0290915 Q9VP76 Drosophila melanogaster
FBpp0298356 Q9VV68 Drosophila melanogaster
FBpp0298357 A8JNU1 Drosophila melanogaster
KCNAB_DROME P17970 Drosophila melanogaster
A1Z6P8_DROME A1Z6P8 Drosophila melanogaster
Q9Y1V0_DROME Q9Y1V0 Drosophila melanogaster
Q7KLG6_DROME Q7KLG6 Drosophila melanogaster
D3DMC8 Drosophila melanogaster