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Author :

Name  Jaynes JB

30 Publications

First Author Title Year Journal Volume Pages PubMed ID
Fujioka M A chromatin insulator mediates transgene homing and very long-range enhancer-promoter communication. 2009 Development 136 3077-87 19675129
Petruk S Transcription of bxd noncoding RNAs promoted by trithorax represses Ubx in cis by transcriptional interference. 2006 Cell 127 1209-21 17174895
Jaynes JB Active repression of transcription by the engrailed homeodomain protein. 1991 EMBO J 10 1427-33 1673924
Johnston DM Ecdysone- and NO-mediated gene regulation by competing EcR/Usp and E75A nuclear receptors during Drosophila development. 2011 Mol Cell 44 51-61 21981918
Americo J A complex array of DNA-binding proteins required for pairing-sensitive silencing by a polycomb group response element from the Drosophila engrailed gene. 2002 Genetics 160 1561-71 11973310
Fujioka M The DNA-binding Polycomb-group protein Pleiohomeotic maintains both active and repressed transcriptional states through a single site. 2008 Development 135 4131-9 19029043
Srinivasula SM sickle, a novel Drosophila death gene in the reaper/hid/grim region, encodes an IAP-inhibitory protein. 2002 Curr Biol 12 125-30 11818063
Fujioka M Regulation of a duplicated locus: Drosophila sloppy paired is replete with functionally overlapping enhancers. 2012 Dev Biol 362 309-19 22178246
Fujioka M Analysis of an even-skipped rescue transgene reveals both composite and discrete neuronal and early blastoderm enhancers, and multi-stripe positioning by gap gene repressor gradients. 1999 Development 126 2527-38 10226011
Fujioka M Early even-skipped stripes act as morphogenetic gradients at the single cell level to establish engrailed expression. 1995 Development 121 4371-82 8575337
Sedkov Y Methylation at lysine 4 of histone H3 in ecdysone-dependent development of Drosophila. 2003 Nature 426 78-83 14603321
Park Y Drosophila homeobox gene eve enhances trol, an activator of neuroblast proliferation in the larval CNS. 1998 Dev Genet 23 247-57 9842718
Fujioka M Engrailed cooperates directly with Extradenticle and Homothorax on a distinct class of homeodomain binding sites to repress sloppy paired. 2012 Dev Biol 366 382-92 22537495
John A Inserting the Ftz homeodomain into engrailed creates a dominant transcriptional repressor that specifically turns off Ftz target genes in vivo. 1995 Development 121 1801-13 7600995
Fujioka M The repressor activity of Even-skipped is highly conserved, and is sufficient to activate engrailed and to regulate both the spacing and stability of parasegment boundaries. 2002 Development 129 4411-21 12223400
Jaynes JB Drawing lines in the sand: even skipped et al. and parasegment boundaries. 2004 Dev Biol 269 609-22 15110723
Kobayashi M Groucho augments the repression of multiple Even skipped target genes in establishing parasegment boundaries. 2001 Development 128 1805-15 11311161
Baines RA Postsynaptic expression of tetanus toxin light chain blocks synaptogenesis in Drosophila. 1999 Curr Biol 9 1267-70 10556094
Kobayashi M Engrailed cooperates with extradenticle and homothorax to repress target genes in Drosophila. 2003 Development 130 741-51 12506004
Han Z Transcriptional integration of competence modulated by mutual repression generates cell-type specificity within the cardiogenic mesoderm. 2002 Dev Biol 252 225-40 12482712
Zhu W Drosophila SAP18, a member of the Sin3/Rpd3 histone deacetylase complex, interacts with Bicoid and inhibits its activity. 2001 Dev Genes Evol 211 109-17 11455422
Park Y even skipped is required to produce a trans-acting signal for larval neuroblast proliferation that can be mimicked by ecdysone. 2001 Development 128 1899-909 11311169
Fujioka M Even-skipped, acting as a repressor, regulates axonal projections in Drosophila. 2003 Development 130 5385-400 13129849
Landgraf M Embryonic origins of a motor system: motor dendrites form a myotopic map in Drosophila. 2003 PLoS Biol 1 E41 14624243
McDonald JA Specification of motoneuron fate in Drosophila: integration of positive and negative transcription factor inputs by a minimal eve enhancer. 2003 J Neurobiol 57 193-203 14556285
Smith ST A conserved region of engrailed, shared among all en-, gsc-, Nk1-, Nk2- and msh-class homeoproteins, mediates active transcriptional repression in vivo. 1996 Development 122 3141-50 8898227
Khan FS The interaction of DIAP1 with dOmi/HtrA2 regulates cell death in Drosophila. 2008 Cell Death Differ 15 1073-83 18259196
Jaynes JB Activation and repression of transcription by homoeodomain-containing proteins that bind a common site. 1988 Nature 336 744-9 2905023
Tolkunova EN Two distinct types of repression domain in engrailed: one interacts with the groucho corepressor and is preferentially active on integrated target genes. 1998 Mol Cell Biol 18 2804-14 9566899
Lacin H Genome-wide identification of Drosophila Hb9 targets reveals a pivotal role in directing the transcriptome within eight neuronal lineages, including activation of nitric oxide synthase and Fd59a/Fox-D. 2014 Dev Biol 388 117-33 24512689