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Protein Domain : IPR012883

Name  ERp29, N-terminal Short Name  ERp29_N
Type  Domain Description  ERp29 () is a ubiquitously expressed endoplasmic reticulum protein, and is involved in the processes of protein maturation and protein secretion in this organelle [, ]. The protein exists as a homodimer, with each monomer being composed of two domains. The N-terminal domain featured in this family is organised into a thioredoxin-like fold that resembles the a domain of human protein disulphide isomerase (PDI) []. However, this domain lacks the C-X-X-C motif required for the redox function of PDI; it is therefore thought that the function of ERp29 is similar to the chaperone function of PDI []. The N-terminal domain is exclusively responsible for the homodimerisation of the protein, without covalent linkages or additional contacts with other domains [].

Publication Counts Displayer

0 Child Features

1 Contains

DB identifier Name Short Name Type
IPR012336 Thioredoxin-like fold Thioredoxin-like_fold Domain

1 Cross References

Identifier
Source . Name

Subject . Primary Identifier
PF07912 PFAM IPR012883

3 Data Sets

Name URL
TrEMBL data set http://www.ebi.ac.uk/trembl/
InterPro data set  
InterPro GO Annotation data set  

1 Found In

DB identifier Name Short Name Type
IPR016855 Endoplasmic reticulum, protein ERp29 ER_p29 Family

2 GO Annotation


Subject . Secondary Identifier

Subject . Name

Subject . Symbol

Ontology Term . Identifier

Ontology Term . Name
ERp29, N-terminal   GO:0009306 protein secretion
ERp29, N-terminal   GO:0005788 endoplasmic reticulum lumen

2 Ontology Annotations


Subject . Secondary Identifier

Subject . Name

Subject . Symbol

Ontology Term . Identifier

Ontology Term . Name
ERp29, N-terminal   GO:0009306 protein secretion
ERp29, N-terminal   GO:0005788 endoplasmic reticulum lumen

0 Parent Features

6 Proteins

DB identifier Primary Accession
Organism . Name
FBpp0085698 O44342 Drosophila melanogaster
FBpp0273953 B5DV07 Drosophila pseudoobscura
FBpp0278058 Q28Z96 Drosophila pseudoobscura
FBpp0168136 B4KU64 Drosophila mojavensis
FBpp0234191 B4MCP5 Drosophila virilis
FBpp0257037 B4PBP3 Drosophila yakuba