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Protein Domain : IPR004842

Name  Na/K/Cl co-transporter superfamily Short Name  Na/K/Cl_cotransptS
Type  Family Description  This is a family of K-Cl cotransporters. It includes bumetanide-sensitive sodium-(potassium)-chloride cotransporter, an electrically silent transporter system which is a mediator of sodium and chloride reabsorption. It plays a vital role in the regulation of ionic balance and cell volume. Bumetanide-sensitive sodium-(potassium)-chloride cotransporter belongs to the SLC12A family of transporters.

Publication Counts Displayer

3 Child Features

DB identifier Name Short Name Type
IPR002443 Na/K/Cl co-transporter Na/K/Cl_cotranspt Family
IPR000076 K-Cl co-transporter KCL_cotranspt Family
IPR002948 Thiazide-sensitive Na-K-Cl co-transporter NaCl_cotranspt Family

3 Contains

DB identifier Name Short Name Type
IPR004841 Amino acid permease/ SLC12A domain AA-permease/SLC12A_dom Domain
IPR013612 Amino acid permease, N-terminal AA_permease_N Domain
IPR018491 K/Cl co-transporter, type 1/type 3 K/Cl_cotranspt_1/3 Domain

1 Cross References

Identifier
Source . Name

Subject . Primary Identifier
TIGR00930 TIGRFAMs IPR004842

3 Data Sets

Name URL
TrEMBL data set http://www.ebi.ac.uk/trembl/
InterPro data set  
InterPro GO Annotation data set  

0 Found In

3 GO Annotation


Subject . Secondary Identifier

Subject . Name

Subject . Symbol

Ontology Term . Identifier

Ontology Term . Name
Na/K/Cl co-transporter superfamily   GO:0015377 cation:chloride symporter activity
Na/K/Cl co-transporter superfamily   GO:0006811 ion transport
Na/K/Cl co-transporter superfamily   GO:0016021 integral component of membrane

3 Ontology Annotations


Subject . Secondary Identifier

Subject . Name

Subject . Symbol

Ontology Term . Identifier

Ontology Term . Name
Na/K/Cl co-transporter superfamily   GO:0015377 cation:chloride symporter activity
Na/K/Cl co-transporter superfamily   GO:0006811 ion transport
Na/K/Cl co-transporter superfamily   GO:0016021 integral component of membrane

0 Parent Features

28 Proteins

DB identifier Primary Accession
Organism . Name
FBpp0078412 Q9VNC6 Drosophila melanogaster
FBpp0078411 Q9VNC7 Drosophila melanogaster
FBpp0075719 Q9VTW8 Drosophila melanogaster
FBpp0072047 Q8MKK5 Drosophila melanogaster
FBpp0309964 Q8MLQ5 Drosophila melanogaster
FBpp0072048 Q9W1G5 Drosophila melanogaster
FBpp0072045 Q9W1G6 Drosophila melanogaster
FBpp0305972 M9PCA7 Drosophila melanogaster
FBpp0305974 M9PI37 Drosophila melanogaster
FBpp0274588 Q2M0N5 Drosophila pseudoobscura
FBpp0277359 Q292Q2 Drosophila pseudoobscura
FBpp0284417 Q296F6 Drosophila pseudoobscura
FBpp0300592 I5APC5 Drosophila pseudoobscura
FBpp0169934 B4KMC3 Drosophila mojavensis
FBpp0173712 B4KD91 Drosophila mojavensis
FBpp0226643 B4LFG0 Drosophila virilis
FBpp0236302 B4LNZ4 Drosophila virilis
FBpp0238978 B4LZB6 Drosophila virilis
FBpp0259351 B4PA99 Drosophila yakuba
FBpp0265137 B4PGC5 Drosophila yakuba
FBpp0270285 B4PVA9 Drosophila yakuba
G0P0P1_CAEBE G0P0P1 Caenorhabditis brenneri
G5EEC9_CAEEL G5EEC9 Caenorhabditis elegans
L8E912_CAEEL L8E912 Caenorhabditis elegans
G5EEQ4_CAEEL G5EEQ4 Caenorhabditis elegans
H8ESD5_CAEEL H8ESD5 Caenorhabditis elegans
H8ESD4_CAEEL H8ESD4 Caenorhabditis elegans
E3NJ77_CAERE E3NJ77 Caenorhabditis remanei