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Protein Domain : IPR018011

Name  Carbohydrate sulfotransferase-related Short Name  Carb_sulfotransferase-rel
Type  Family Description  This entry consists of a number of carbohydrate sulphotransferases that transfer sulphate to carbohydrate groups in glycoproteins and glycolipids. These include:Carbohydrate sulphotransferases 8 and 9, which transfer sulphate to position 4 of non-reducing N-acetylgalactosamine (GalNAc) residues in both N-glycans and O-glycans []. They function in the biosynthesis of glycoprotein hormones lutropin and thyrotropin, by mediating sulphation of their carbohydrate structures.Carbohydrate sulphotransferase 10, which transfers sulphate to position 3 of the terminal glucuronic acid in both protein- and lipid-linked oligosaccharides []. It directs the biosynthesis of the HNK-1 carbohydrate structure, a sulphated glucuronyl-lactosaminyl residue carried by many neural recognition molecules, which is involved in cell interactions during ontogenetic development and in synaptic plasticity in the adult.Carbohydrate sulphotransferases 11 - 13, which catalyze the transfer of sulphate to position 4 of the GalNAc residue of chondroitin []. Chondroitin sulphate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices. Some, thought not all, of these enzymes also transfer sulphate to dermatan.Carbohydrate sulphotransferase D4ST1, which transfers sulphate to position 4 of the GalNAc residue of dermatan sulphate [].

Publication Counts Displayer

0 Child Features

0 Contains

1 Cross References

Identifier
Source . Name

Subject . Primary Identifier
PTHR12137 PANTHER IPR018011

3 Data Sets

Name URL
TrEMBL data set http://www.ebi.ac.uk/trembl/
InterPro data set  
InterPro GO Annotation data set  

0 Found In

3 GO Annotation


Subject . Secondary Identifier

Subject . Name

Subject . Symbol

Ontology Term . Identifier

Ontology Term . Name
Carbohydrate sulfotransferase-related   GO:0008146 sulfotransferase activity
Carbohydrate sulfotransferase-related   GO:0016051 carbohydrate biosynthetic process
Carbohydrate sulfotransferase-related   GO:0016021 integral component of membrane

3 Ontology Annotations


Subject . Secondary Identifier

Subject . Name

Subject . Symbol

Ontology Term . Identifier

Ontology Term . Name
Carbohydrate sulfotransferase-related   GO:0008146 sulfotransferase activity
Carbohydrate sulfotransferase-related   GO:0016051 carbohydrate biosynthetic process
Carbohydrate sulfotransferase-related   GO:0016021 integral component of membrane

1 Parent Features

DB identifier Name Short Name Type
IPR005331 Sulfotransferase Sulfotransferase Family

21 Proteins

DB identifier Primary Accession
Organism . Name
FBpp0080500 Q9VJG5 Drosophila melanogaster
FBpp0078716 Q9VMS3 Drosophila melanogaster
FBpp0289941 Q8IRG5 Drosophila melanogaster
FBpp0289938 Q9W070 Drosophila melanogaster
FBpp0304915 M9PBI7 Drosophila melanogaster
FBpp0279851 Q29M12 Drosophila pseudoobscura
FBpp0274439 Q2M058 Drosophila pseudoobscura
FBpp0278468 Q29L92 Drosophila pseudoobscura
FBpp0161224 B4KWW3 Drosophila mojavensis
FBpp0159792 B4KI39 Drosophila mojavensis
FBpp0171747 B4KLJ6 Drosophila mojavensis
FBpp0227694 B4LH09 Drosophila virilis
FBpp0236198 B4LRA7 Drosophila virilis
FBpp0237463 B4LV81 Drosophila virilis
FBpp0257787 B4P980 Drosophila yakuba
FBpp0260205 B4IWG4 Drosophila yakuba
FBpp0264015 B4P075 Drosophila yakuba
FBpp0265914 B4PDW0 Drosophila yakuba
FBpp0267867 B4ITY2 Drosophila yakuba
FBpp0267871 B4ITX9 Drosophila yakuba
Q6NNF1_DROME Q6NNF1 Drosophila melanogaster