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Protein Domain : IPR013625

Name  Tensin phosphotyrosine-binding domain Short Name  PTB
Type  Domain Description  The phosphotyrosine-binding domain (PTB, also phosphotyrosine-interaction or PI domain) of tensin tends to be found at the C terminus of a protein.Tensin is a multi-domain protein that binds to actin filaments and functions as a focal-adhesion molecule (focal adhesions are regions of plasma membrane through which cells attach to the extracellular matrix). Human tensin has actin-binding sites, an SH2 () domain and a region similar to the tumour suppressor PTEN []. The PTB domain interacts with the cytoplasmic tails of beta integrin by binding to an NPXY motif [].

Publication Counts Displayer

0 Child Features

0 Contains

1 Cross References

Identifier
Source . Name

Subject . Primary Identifier
PF08416 PFAM IPR013625

3 Data Sets

Name URL
TrEMBL data set http://www.ebi.ac.uk/trembl/
InterPro data set  
InterPro GO Annotation data set  

1 Found In

DB identifier Name Short Name Type
IPR011993 Pleckstrin homology-like domain PH_like_dom Domain

1 GO Annotation


Subject . Secondary Identifier

Subject . Name

Subject . Symbol

Ontology Term . Identifier

Ontology Term . Name
Tensin phosphotyrosine-binding domain   GO:0005515 protein binding

1 Ontology Annotations


Subject . Secondary Identifier

Subject . Name

Subject . Symbol

Ontology Term . Identifier

Ontology Term . Name
Tensin phosphotyrosine-binding domain   GO:0005515 protein binding

0 Parent Features

37 Proteins

DB identifier Primary Accession
Organism . Name
FBpp0081597 Q9VHC3 Drosophila melanogaster
FBpp0082815 Q95TJ6 Drosophila melanogaster
FBpp0077697 Q8IPW1 Drosophila melanogaster
FBpp0077696 Q9VPU7 Drosophila melanogaster
FBpp0293795 H9ZYQ1 Drosophila melanogaster
FBpp0279929 Q29M78 Drosophila pseudoobscura
FBpp0284195 Q297I5 Drosophila pseudoobscura
FBpp0284487 B5DYC5 Drosophila pseudoobscura
FBpp0167225 B4KF67 Drosophila mojavensis
FBpp0171814 B4KB65 Drosophila mojavensis
FBpp0173067 B4KC81 Drosophila mojavensis
FBpp0173204 B4K4H9 Drosophila mojavensis
FBpp0224732 B4M429 Drosophila virilis
FBpp0234047 B4LTY5 Drosophila virilis
FBpp0224982 B4M5J9 Drosophila virilis
FBpp0238040 B4LVY7 Drosophila virilis
FBpp0260875 B4P2Y7 Drosophila yakuba
FBpp0269609 B4PM95 Drosophila yakuba
FBpp0269779 B4PUQ0 Drosophila yakuba
A8XKY8_CAEBR A8XKY8 Caenorhabditis briggsae
H2WGX1_CAEJA H2WGX1 Caenorhabditis japonica
H2W0M2_CAEJA H2W0M2 Caenorhabditis japonica
G0PLV8_CAEBE G0PLV8 Caenorhabditis brenneri
G0MNL7_CAEBE G0MNL7 Caenorhabditis brenneri
G0NDQ3_CAEBE G0NDQ3 Caenorhabditis brenneri
G5EFE0_CAEEL G5EFE0 Caenorhabditis elegans
G5ED33_CAEEL G5ED33 Caenorhabditis elegans
H2L046_CAEEL H2L046 Caenorhabditis elegans
Q7YTG1_CAEEL Q7YTG1 Caenorhabditis elegans
P92160_CAEEL P92160 Caenorhabditis elegans