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Protein Domain : IPR001863

Name  Glypican Short Name  Glypican
Type  Family Description  Glypicans [, ]are a family of heparan sulphate proteoglycans which are anchored to cell membranes by a glycosylphosphatidylinositol (GPI) linkage. Six members (GPC1-6) are known in vertebrates []. Structurally, these proteins consist of three separate domains:A signal sequence;An extracellular domain of about 500 residues that contains 12 conserved cysteines probably involved in disulphide bonds and which also contains the sites of attachment of the heparan sulphate glycosaminoglycan side chains;A C-terminal hydrophobic region which is post-translationally removed after formation of the GPI-anchor.

Publication Counts Displayer

2 Child Features

DB identifier Name Short Name Type
IPR015501 Glypican-3 Glypican-3 Family
IPR015502 Glypican-1 Glypican-1 Family

1 Contains

DB identifier Name Short Name Type
IPR019803 Glypican, conserved site Glypican_CS Conserved_site

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
PTHR10822 PANTHER IPR001863
PF01153 PFAM IPR001863

3 Data Sets

Name URL
TrEMBL data set http://www.ebi.ac.uk/trembl/
InterPro data set  
InterPro GO Annotation data set  

0 Found In

3 GO Annotation


Subject . Secondary Identifier

Subject . Name

Subject . Symbol

Ontology Term . Identifier

Ontology Term . Name
Glypican   GO:0043395 heparan sulfate proteoglycan binding
Glypican   GO:0005578 proteinaceous extracellular matrix
Glypican   GO:0016020 membrane

3 Ontology Annotations


Subject . Secondary Identifier

Subject . Name

Subject . Symbol

Ontology Term . Identifier

Ontology Term . Name
Glypican   GO:0043395 heparan sulfate proteoglycan binding
Glypican   GO:0005578 proteinaceous extracellular matrix
Glypican   GO:0016020 membrane

0 Parent Features

19 Proteins

DB identifier Primary Accession
Organism . Name
FBpp0076310 Q24114 Drosophila melanogaster
FBpp0075431 Q9VUG1 Drosophila melanogaster
FBpp0305246 Q7KUL1 Drosophila melanogaster
FBpp0274736 Q2M164 Drosophila pseudoobscura
FBpp0285987 Q29D31 Drosophila pseudoobscura
FBpp0160711 B4KVM4 Drosophila mojavensis
FBpp0162153 B4KZG2 Drosophila mojavensis
FBpp0227494 B4LEP5 Drosophila virilis
FBpp0228106 B4LF40 Drosophila virilis
FBpp0265796 B4PFH8 Drosophila yakuba
FBpp0267030 B4PIF2 Drosophila yakuba
A8X454_CAEBR A8X454 Caenorhabditis briggsae
H2W3M8_CAEJA H2W3M8 Caenorhabditis japonica
H2WNS9_CAEJA H2WNS9 Caenorhabditis japonica
G0MAS5_CAEBE G0MAS5 Caenorhabditis brenneri
G5EGU4_CAEEL G5EGU4 Caenorhabditis elegans
Q966V5_DROME Q966V5 Drosophila melanogaster
Q9GPL5_DROME Q9GPL5 Drosophila melanogaster
E3MJC2_CAERE E3MJC2 Caenorhabditis remanei