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Protein Domain : IPR024733

Name  Alpha-N-acetylglucosaminidase, tim-barrel domain Short Name  NAGLU_tim-barrel
Type  Domain Description  Alpha-N-acetylglucosaminidase is a lysosomal enzyme that is required for the stepwise degradation of heparan sulphate []. Mutations on the alpha-N-acetylglucosaminidase gene can lead to mucopolysaccharidosis type IIIB (MPS IIIB; or Sanfilippo syndrome type B), characterised by neurological dysfunction but relatively mild somatic manifestations [].Alpha-N-acetylglucosaminidase is composed of three domains. This entry represents the central domain, which has a tim barrel fold [].

Publication Counts Displayer

0 Child Features

0 Contains

1 Cross References

Source . Name

Subject . Primary Identifier
PF05089 PFAM IPR024733

2 Data Sets

Name URL
TrEMBL data set
InterPro data set  

0 Found In

0 GO Annotation

0 Ontology Annotations

0 Parent Features

10 Proteins

DB identifier Primary Accession
Organism . Name
FBpp0079316 Q9VLL5 Drosophila melanogaster
FBpp0279438 Q29P00 Drosophila pseudoobscura
FBpp0166458 B4KKH5 Drosophila mojavensis
FBpp0232417 B4M924 Drosophila virilis
FBpp0256001 B4NWZ2 Drosophila yakuba
A8XYS1_CAEBR A8XYS1 Caenorhabditis briggsae
H2VQD6_CAEJA H2VQD6 Caenorhabditis japonica
G0MZ45_CAEBE G0MZ45 Caenorhabditis brenneri
Q9NAP6_CAEEL Q9NAP6 Caenorhabditis elegans
E3MMZ2_CAERE E3MMZ2 Caenorhabditis remanei