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Protein Domain : IPR017849

Name  Alkaline phosphatase-like, alpha/beta/alpha Short Name  Alkaline_Pase-like_a/b/a
Type  Domain Description  This entry represents a structural domain with a 3-layer alpha/beta/alpha structure that forms the core domain of alkaline phosphatases. These enzymes can have several large insertions, but these extra subdomains are not covered by this entry. This structural domain is found in:Alkaline phosphatase (); most use zinc and magnesium as cofactors [, ].Arylsulphatase (has an additional C-terminal alpha+beta subdomain) () [, ].Phosphoglycerate mutase (catalytic domain) () [].Phosphonoacetate hydrolase (contains an alpha+beta subdomain inserted near C terminus) (); uses zinc as a cofactor.

Publication Counts Displayer

0 Child Features

2 Contains

DB identifier Name Short Name Type
IPR006124 Metalloenzyme Metalloenzyme Domain
IPR018299 Alkaline phosphatase, active site Alkaline_phosphatase_AS Active_site

1 Cross References

Identifier
Source . Name

Subject . Primary Identifier
G3DSA:3.40.720.10 GENE3D IPR017849

3 Data Sets

Name URL
TrEMBL data set http://www.ebi.ac.uk/trembl/
InterPro data set  
InterPro GO Annotation data set  

15 Found In

DB identifier Name Short Name Type
IPR017850 Alkaline-phosphatase-like, core domain Alkaline_phosphatase_core Domain
IPR000917 Sulfatase Sulfatase Domain
IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase Phosphodiest/P_Trfase Family
IPR007070 GPI ethanolamine phosphate transferase 1 GPI_EtnP_transferase_1 Family
IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent Pgm_bpd_ind Family
IPR001952 Alkaline phosphatase Alkaline_phosphatase Family
IPR012251 N-acetylglucosamine-6-sulfatase GlcNAc_6-SO4ase Family
IPR020881 Phosphoglycerol transferase I Phosphoglycerol_transferase_I Family
IPR015981 N-acetylglucosamine-6-sulfatase, eukaryotic GlcNAc_6-SO4ase_euk Family
IPR017785 Choline-sulfatase Choline-sulfatase Family
IPR012710 Phosphonoacetate hydrolase Phosphonoacetate_hydro Family
IPR014615 Extracellular sulfatase Extracellular_sulfatase Family
IPR012083 Arylsulfatase Arylsulfatase Family
IPR012159 Membrane sulfatase, HI0842-related Membrane_sulfatase_HI0842 Family
IPR012160 Membrane sulfatase, HI1246-related Membrane_sulfatase_HI1246 Family

2 GO Annotation


Subject . Secondary Identifier

Subject . Name

Subject . Symbol

Ontology Term . Identifier

Ontology Term . Name
Alkaline phosphatase-like, alpha/beta/alpha   GO:0003824 catalytic activity
Alkaline phosphatase-like, alpha/beta/alpha   GO:0008152 metabolic process

2 Ontology Annotations


Subject . Secondary Identifier

Subject . Name

Subject . Symbol

Ontology Term . Identifier

Ontology Term . Name
Alkaline phosphatase-like, alpha/beta/alpha   GO:0003824 catalytic activity
Alkaline phosphatase-like, alpha/beta/alpha   GO:0008152 metabolic process

0 Parent Features

367 Proteins

DB identifier Primary Accession
Organism . Name
FBpp0082576 Q9VF91 Drosophila melanogaster
FBpp0072576 Q9W0F7 Drosophila melanogaster
FBpp0086833 Q5BIL9 Drosophila melanogaster
FBpp0081952 Q9VGG4 Drosophila melanogaster
FBpp0076835 Q9VRM8 Drosophila melanogaster
FBpp0071695 Q9W274 Drosophila melanogaster
FBpp0071696 Q9W275 Drosophila melanogaster
FBpp0074908 Q9VVM1 Drosophila melanogaster
FBpp0077407 Q9VQH3 Drosophila melanogaster
FBpp0077564 Q9VQ50 Drosophila melanogaster
FBpp0084674 Q9VAU4 Drosophila melanogaster
FBpp0087517 A1Z838 Drosophila melanogaster
FBpp0083450 Q9VDG4 Drosophila melanogaster
FBpp0071694 Q9W273 Drosophila melanogaster
FBpp0073864 Q9VXS8 Drosophila melanogaster
FBpp0076794 Q9VRM9 Drosophila melanogaster
FBpp0078050 Q9VP35 Drosophila melanogaster
FBpp0079359 Q86BL8 Drosophila melanogaster
FBpp0083138 Q9VE24 Drosophila melanogaster
FBpp0083374 Q8SY05 Drosophila melanogaster
FBpp0080745 Q9VIW9 Drosophila melanogaster
FBpp0087978 A1Z705 Drosophila melanogaster
FBpp0083723 Q9VCV7 Drosophila melanogaster
FBpp0072939 Q9VZP8 Drosophila melanogaster
FBpp0081538 Q9VHD0 Drosophila melanogaster
FBpp0074909 Q9VVM4 Drosophila melanogaster
FBpp0081936 Q9VGM0 Drosophila melanogaster
FBpp0087603 Q7K3X8 Drosophila melanogaster
FBpp0085283 Q9V9P7 Drosophila melanogaster
FBpp0085870 A1ZB84 Drosophila melanogaster