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Protein Domain : IPR000644

Name  CBS domain Short Name  CBS_dom
Type  Domain Description  CBS domains are small intracellular modules that pair together to form a stable globular domain []. Pairs of these domains have been termed a Bateman domain []. CBS domains have been shown to bind ligands with an adenosyl group such as AMP, ATP and S-AdoMet []. CBS domains are found attached to a wide range of other protein domains suggesting that CBS domains may play a regulatory role making proteins sensitive to adenosyl carrying ligands. The region containing the CBS domains in cystathionine-beta synthase is involved in regulation by S-AdoMet []. CBS domain pairs from AMPK bind AMP or ATP []. The CBS domains from IMPDH and the chloride channel CLC2 bind ATP [].

Publication Counts Displayer

0 Child Features

0 Contains

3 Cross References

Identifier
Source . Name

Subject . Primary Identifier
PF00571 PFAM IPR000644
PS51371 PROFILE IPR000644
SM00116 SMART IPR000644

3 Data Sets

Name URL
TrEMBL data set http://www.ebi.ac.uk/trembl/
InterPro data set  
InterPro GO Annotation data set  

25 Found In

DB identifier Name Short Name Type
IPR001093 IMP dehydrogenase/GMP reductase IMP_DH_GMPRt Domain
IPR005990 Inosine-5'-monophosphate dehydrogenase IMP_DH Family
IPR001807 Chloride channel, voltage gated Cl-channel_volt-gated Family
IPR005857 Cystathionine beta-synthase Cysta_beta_synth Family
IPR019862 Gliding motility-associated protein GldE Motility-assoc_prot_GldE Family
IPR005991 IMP dehydrogenase-related 1 IMP_DH-rel1 Family
IPR016427 Uncharacterised conserved protein UCP004699, CBS/ParB-like UCP004699_CBS/ParB Family
IPR016436 Uncharacterised conserved protein UCP005063, CBS-type UCP005063_CBS Family
IPR016486 Uncharacterised conserved protein UCP006591, CBS-type UCP006591_CBS Family
IPR014651 Uncharacterised conserved protein, 2xCBS, MJ1404 type UCP036983_2CBS_MJ1404 Family
IPR016426 Uncharacterised conserved protein UCP004698, CBS-type UCP004698_CBS_type Family
IPR012157 Uncharacterised conserved protein, CBS/CP12 UCP_CBS_CP12 Family
IPR005892 Glycine betaine transport ATP-binding subunit Gly-betaine_transp_ATP-bd Family
IPR016842 Uncharacterised conserved protein UCP026546, HtH-CBS UCP026546_HTH-CBS Family
IPR017080 Uncharacterised conserved protein UCP036990, CBS, BON UCP036990_CBS_BON Family
IPR017036 Uncharacterised conserved protein UCP035040, CBS-type UCP035040_CBS Family
IPR017158 Transcription regulator, CBS domain-containing, predicted Tscrpt-reg_CBS-contain_prd Family
IPR004800 Phosphosugar isomerase, KdsD/KpsF-type KdsD/KpsF-type Family
IPR002243 Chloride channel ClC-1 Cl_channel-1 Family
IPR002246 Chloride channel ClC-4 Cl_channel-4 Family
IPR002247 Chloride channel ClC-5 Cl_channel-5 Family
IPR016483 Uncharacterised conserved protein UCP006404, peptidase M50/CBS UCP006404_Pept_M50_CBS Family
IPR016711 Sds23 Ssd23 Family
IPR016761 Uncharacterised conserved protein UCP019454, CBS UCP019454_CBS Family
IPR006669 Divalent cation transporter MgtE_transporter Family

1 GO Annotation


Subject . Secondary Identifier

Subject . Name

Subject . Symbol

Ontology Term . Identifier

Ontology Term . Name
CBS domain   GO:0030554 adenyl nucleotide binding

1 Ontology Annotations


Subject . Secondary Identifier

Subject . Name

Subject . Symbol

Ontology Term . Identifier

Ontology Term . Name
CBS domain   GO:0030554 adenyl nucleotide binding

0 Parent Features

158 Proteins

DB identifier Primary Accession
Organism . Name
FBpp0290800 A1A703 Drosophila melanogaster
FBpp0290804 Q9VDD2 Drosophila melanogaster
FBpp0290802 Q8SXT8 Drosophila melanogaster
FBpp0110237 Q0KI34 Drosophila melanogaster
FBpp0071424 Q07152 Drosophila melanogaster
FBpp0083422 Q7JQX9 Drosophila melanogaster
FBpp0083427 Q8I0A1 Drosophila melanogaster
FBpp0112303 H1UUP0 Drosophila melanogaster
FBpp0082002 Q9VGH7 Drosophila melanogaster
FBpp0309380 Q9VRD9 Drosophila melanogaster
FBpp0291437 A8Y516 Drosophila melanogaster
FBpp0075201 Q8IQN2 Drosophila melanogaster
FBpp0291665 Q9VUY1 Drosophila melanogaster
FBpp0086939 Q7JZ25 Drosophila melanogaster
FBpp0301252 I5APM5 Drosophila pseudoobscura
FBpp0301251 I5APM4 Drosophila pseudoobscura
FBpp0301250 Q294Z4 Drosophila pseudoobscura
FBpp0301249 I5APM3 Drosophila pseudoobscura
FBpp0301248 I5APM2 Drosophila pseudoobscura
FBpp0272303 Q29FV1 Drosophila pseudoobscura
FBpp0273501 Q29IQ0 Drosophila pseudoobscura
FBpp0274691 Q2M106 Drosophila pseudoobscura
FBpp0301086 B5DVX1 Drosophila pseudoobscura
FBpp0301087 I5APL8 Drosophila pseudoobscura
FBpp0276228 Q28YH2 Drosophila pseudoobscura
FBpp0159359 B4KB38 Drosophila mojavensis
FBpp0162289 B4L0Z1 Drosophila mojavensis
FBpp0164650 B4L2S4 Drosophila mojavensis
FBpp0168342 B4KQT5 Drosophila mojavensis
FBpp0172199 B4K570 Drosophila mojavensis