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Protein Domain : IPR013767

Name  PAS fold Short Name  PAS_fold
Type  Domain Description  PAS domains are involved in many signalling proteins where theyare used as a signal sensor domain []. PAS domains appear in archaea,bacteria and eukaryotes. Several PAS-domain proteins are known todetect their signal by way of an associated cofactor. Haeme,flavin, and a 4-hydroxycinnamyl chromophore are used in differentproteins. The PAS domain was named after three proteins that itoccurs in: Per- period circadian proteinArnt- Ah receptor nuclear translocator proteinSim- single-minded protein.PAS domains are often associated withPAC domains . It appears that these domains are directly linked, and that together they form the conserved 3D PAS fold. The division between the PAS and PAC domains is caused by major differences in sequences in the region connecting these two motifs []. In human PAS kinase, this region has been shown to be very flexible, and adopts different conformations depending on the bound ligand [].Probably the most surprising identification of a PAS domain was that inEAG-like K+-channels [].

Publication Counts Displayer

0 Child Features

2 Contains

DB identifier Name Short Name Type
IPR001610 PAC motif PAC Repeat
IPR000700 PAS-associated, C-terminal PAS-assoc_C Domain

1 Cross References

Identifier
Source . Name

Subject . Primary Identifier
PF00989 PFAM IPR013767

3 Data Sets

Name URL
TrEMBL data set http://www.ebi.ac.uk/trembl/
InterPro data set  
InterPro GO Annotation data set  

12 Found In

DB identifier Name Short Name Type
IPR003949 Potassium channel, voltage-dependent, EAG K_chnl_volt-dep_EAG Family
IPR001067 Nuclear translocator Nuc_translocat Family
IPR017426 Nuclear receptor coactivator Nuclear_rcpt_coactivator Family
IPR011785 Transcription regulator PpsR Tscrpt_reg_PpsR-CrtJ Family
IPR012226 Oxygen sensor diguanylate cyclase/c-di-GMP phosphodiesterase Dos Family
IPR001294 Phytochrome Phytochrome Family
IPR014285 Nitrogen fixation negative regulator NifL N_fixation_neg-reg_NifL Family
IPR014409 Signal transduction histidine kinase, hybrid-type, aerobic respiration control ArcB Sig_transdc_His_kin_hyb_ArcB Family
IPR014310 Signal transduction histidine kinase, phosphate regulon sensor PhoR Sig_transdc_His_kinase_PhoR Family
IPR012129 Phytochrome A/B/C/D/E Phytochrome_A-E Family
IPR012130 Photoactive yellow-protein PYP Family
IPR016384 Plasmid transfer regulator TraJ, R1 plasmid TraJ_R1 Family

1 GO Annotation


Subject . Secondary Identifier

Subject . Name

Subject . Symbol

Ontology Term . Identifier

Ontology Term . Name
PAS fold   GO:0006355 regulation of transcription, DNA-templated

1 Ontology Annotations


Subject . Secondary Identifier

Subject . Name

Subject . Symbol

Ontology Term . Identifier

Ontology Term . Name
PAS fold   GO:0006355 regulation of transcription, DNA-templated

1 Parent Features

DB identifier Name Short Name Type
IPR000014 PAS domain PAS Domain

84 Proteins

DB identifier Primary Accession
Organism . Name
FBpp0070455 M9PGJ3 Drosophila melanogaster
FBpp0081483 O15945 Drosophila melanogaster
FBpp0074693 O61734 Drosophila melanogaster
FBpp0082768 Q9VEV9 Drosophila melanogaster
FBpp0310748 B7Z0S3 Drosophila melanogaster
FBpp0310747 Q24167 Drosophila melanogaster
FBpp0293064 H9TV77 Drosophila melanogaster
FBpp0303179 Q24119 Drosophila melanogaster
FBpp0306033 M9PDQ7 Drosophila melanogaster
FBpp0306032 M9PE27 Drosophila melanogaster
FBpp0303180 M9PDI8 Drosophila melanogaster
FBpp0283113 Q29C65 Drosophila pseudoobscura
FBpp0277906 Q29FF1 Drosophila pseudoobscura
FBpp0282234 B5DXT9 Drosophila pseudoobscura
FBpp0284700 P12348 Drosophila pseudoobscura
FBpp0284790 Q294H9 Drosophila pseudoobscura
FBpp0300706 I5APE8 Drosophila pseudoobscura
FBpp0165512 B4L632 Drosophila mojavensis
FBpp0162884 B4L0X6 Drosophila mojavensis
FBpp0159392 B4KBU3 Drosophila mojavensis
FBpp0164048 B4L4N5 Drosophila mojavensis
FBpp0165953 B4L8X9 Drosophila mojavensis
FBpp0172586 B4K8H0 Drosophila mojavensis
FBpp0172864 B4KDN6 Drosophila mojavensis
FBpp0224781 B4M6L5 Drosophila virilis
FBpp0225201 B4M6I9 Drosophila virilis
FBpp0225293 B4M453 Drosophila virilis
FBpp0226899 B4LCU8 Drosophila virilis
FBpp0231099 B4M816 Drosophila virilis
FBpp0237907 B4LWW7 Drosophila virilis