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Protein Domain : IPR018456

Name  PTR2 family proton/oligopeptide symporter, conserved site Short Name  PTR2_symporter_CS
Type  Conserved_site Description  The transport of peptides into cells is a well-documented biological phenomenon which is accomplished by specific, energy-dependent transporters found in a number of organisms as diverse as bacteria and humans. The PTR family of proteins is distinct from the ABC-type peptide transporters and was uncovered by sequence analyses of a number of recently discovered peptide transport proteins []. These proteins that seem to be mainly involved in the intake of small peptides with the concomitant uptake of a proton [].These integral membrane proteins are predicted to comprise twelvetransmembrane regions.This entry describes two conserved sites. The first conserved site is found within a region that includes the end of the second transmembrane region, a cytoplasmic loop as well as the third transmembrane region. The second conserved site corresponds to the core of the fifth transmembrane region.

Publication Counts Displayer

0 Child Features

0 Contains

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
PS01022 PROSITE IPR018456
PS01023 PROSITE IPR018456

3 Data Sets

Name URL
TrEMBL data set http://www.ebi.ac.uk/trembl/
InterPro data set  
InterPro GO Annotation data set  

4 Found In

DB identifier Name Short Name Type
IPR020846 Major facilitator superfamily domain MFS_dom Domain
IPR016196 Major facilitator superfamily domain, general substrate transporter MFS_dom_general_subst_transpt Domain
IPR000109 Proton-dependent oligopeptide transporter family POT_fam Family
IPR005279 Amino acid/peptide transporter family AA/pep_transptr Family

3 GO Annotation


Subject . Secondary Identifier

Subject . Name

Subject . Symbol

Ontology Term . Identifier

Ontology Term . Name
PTR2 family proton/oligopeptide symporter, conserved site   GO:0005215 transporter activity
PTR2 family proton/oligopeptide symporter, conserved site   GO:0006857 oligopeptide transport
PTR2 family proton/oligopeptide symporter, conserved site   GO:0016020 membrane

3 Ontology Annotations


Subject . Secondary Identifier

Subject . Name

Subject . Symbol

Ontology Term . Identifier

Ontology Term . Name
PTR2 family proton/oligopeptide symporter, conserved site   GO:0005215 transporter activity
PTR2 family proton/oligopeptide symporter, conserved site   GO:0006857 oligopeptide transport
PTR2 family proton/oligopeptide symporter, conserved site   GO:0016020 membrane

0 Parent Features

36 Proteins

DB identifier Primary Accession
Organism . Name
FBpp0070583 Q9W4P6 Drosophila melanogaster
FBpp0070581 Q8IRT1 Drosophila melanogaster
FBpp0081577 Q9VH93 Drosophila melanogaster
FBpp0309179 P91679 Drosophila melanogaster
FBpp0272806 B5DN49 Drosophila pseudoobscura
FBpp0280994 Q29GY1 Drosophila pseudoobscura
FBpp0167220 B4KF56 Drosophila mojavensis
FBpp0165267 B4L740 Drosophila mojavensis
FBpp0165695 B4L741 Drosophila mojavensis
FBpp0229977 B4MB13 Drosophila virilis
FBpp0230439 B4MB14 Drosophila virilis
FBpp0261327 B4Q0H6 Drosophila yakuba
FBpp0261894 B4Q0H7 Drosophila yakuba
FBpp0269760 B4PVC5 Drosophila yakuba
A8XXG2_CAEBR A8XXG2 Caenorhabditis briggsae
A8XRM9_CAEBR A8XRM9 Caenorhabditis briggsae
A8WZ37_CAEBR A8WZ37 Caenorhabditis briggsae
H2WJF7_CAEJA H2WJF7 Caenorhabditis japonica
K7GZV1_CAEJA K7GZV1 Caenorhabditis japonica
K7GZV0_CAEJA K7GZV0 Caenorhabditis japonica
H2VHZ0_CAEJA H2VHZ0 Caenorhabditis japonica
G0NG16_CAEBE G0NG16 Caenorhabditis brenneri
G0P5W6_CAEBE G0P5W6 Caenorhabditis brenneri
G0NH62_CAEBE G0NH62 Caenorhabditis brenneri
G0MSQ6_CAEBE G0MSQ6 Caenorhabditis brenneri
PEPT1_CAEEL Q21219 Caenorhabditis elegans
PEPT2_CAEEL Q17758 Caenorhabditis elegans
PEPT3_CAEEL O01840 Caenorhabditis elegans
PEPT1_DROME-2 P91679-2 Drosophila melanogaster
PEPT1_DROME-3 P91679-3 Drosophila melanogaster