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Protein Domain : IPR017304

Name  Cytoplasmic protein NCK Short Name  NCK
Type  Family Description  Cytoplasmic protein NCK (NCK) is a family of non-enzymatic adaptor proteins composed of three SH3 (Src homology 3) domains and a C-terminal SH2 domain []. They associate with tyrosine-phosphorylated growth factor receptors or their cellular substrates [,]. They are implicated in organisation of actin cytoskeleton, cell movement or axon guidance []. There are two vertebrate NCK proteins, NCK1 and NCK2.

Publication Counts Displayer

2 Child Features

DB identifier Name Short Name Type
IPR028524 Cytoplasmic protein NCK2 NCK2 Family
IPR028526 Cytoplasmic protein NCK1 NCK1 Family

2 Contains

DB identifier Name Short Name Type
IPR000980 SH2 domain SH2 Domain
IPR001452 SH3 domain SH3_domain Domain

1 Cross References

Source . Name

Subject . Primary Identifier
PIRSF037874 PIRSF IPR017304

2 Data Sets

Name URL
TrEMBL data set
InterPro data set  

0 Found In

0 GO Annotation

0 Ontology Annotations

0 Parent Features

7 Proteins

DB identifier Primary Accession
Organism . Name
FBpp0077678 Q8IPW2 Drosophila melanogaster
A8XJT7_CAEBR A8XJT7 Caenorhabditis briggsae
H2VW83_CAEJA H2VW83 Caenorhabditis japonica
G0M7Y3_CAEBE G0M7Y3 Caenorhabditis brenneri
Q95PW9_CAEEL Q95PW9 Caenorhabditis elegans
Q24218_DROME Q24218 Drosophila melanogaster
E3LEM6_CAERE E3LEM6 Caenorhabditis remanei