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Protein Domain : IPR008379

Name  Band 4.1, C-terminal Short Name  Band_4.1_C
Type  Domain Description  There is a unique sequence domain at the C terminus of all known 4.1 proteins, known as the C-terminal domain (CTD). Mammalian CTDs are associated with a growing number of protein-protein interactions, although such activities have yet to be associated with invertebrate CTDs. Mammalian CTDs are generally defined by sequence alignment as encoded by exons 18-21. Comparison of known vertebrate 4.1 proteins with invertebrate 4.1 proteins indicates that mammalian 4.1 exon 19 represents a vertebrate adaptation that extends the sequence of the CTD with a Ser/Thr-rich sequence. The CTD was first described as a 22/24 kDa domain by chymotryptic digestion of erythrocyte 4.1 (4.1R). CTD is thought to represent an independent folding structure which has gained function since the divergence of vertebrates from invertebrates [].

Publication Counts Displayer

0 Child Features

0 Contains

1 Cross References

Identifier
Source . Name

Subject . Primary Identifier
PF05902 PFAM IPR008379

3 Data Sets

Name URL
TrEMBL data set http://www.ebi.ac.uk/trembl/
InterPro data set  
InterPro GO Annotation data set  

2 Found In

DB identifier Name Short Name Type
IPR000798 Ezrin/radixin/moesin like Ez/rad/moesin_like Family
IPR021187 Band 4.1 protein Band_41_protein Family

3 GO Annotation


Subject . Secondary Identifier

Subject . Name

Subject . Symbol

Ontology Term . Identifier

Ontology Term . Name
Band 4.1, C-terminal   GO:0003779 actin binding
Band 4.1, C-terminal   GO:0005198 structural molecule activity
Band 4.1, C-terminal   GO:0005856 cytoskeleton

3 Ontology Annotations


Subject . Secondary Identifier

Subject . Name

Subject . Symbol

Ontology Term . Identifier

Ontology Term . Name
Band 4.1, C-terminal   GO:0003779 actin binding
Band 4.1, C-terminal   GO:0005198 structural molecule activity
Band 4.1, C-terminal   GO:0005856 cytoskeleton

0 Parent Features

23 Proteins

DB identifier Primary Accession
Organism . Name
FBpp0085697 Q9V8R9 Drosophila melanogaster
FBpp0290494 H5V8A7 Drosophila melanogaster
FBpp0309093 Q28Z97 Drosophila pseudoobscura
FBpp0309094 N6WBW7 Drosophila pseudoobscura
FBpp0308184 N6VF07 Drosophila pseudoobscura
FBpp0308185 N6V854 Drosophila pseudoobscura
FBpp0168135 B4KU65 Drosophila mojavensis
FBpp0234190 B4MCP4 Drosophila virilis
FBpp0257036 B4PBP4 Drosophila yakuba
A8X7B8_CAEBR A8X7B8 Caenorhabditis briggsae
H2VT42_CAEJA H2VT42 Caenorhabditis japonica
G0NCH7_CAEBE G0NCH7 Caenorhabditis brenneri
G0NZM4_CAEBE G0NZM4 Caenorhabditis brenneri
G5EEG8_CAEEL G5EEG8 Caenorhabditis elegans
G5EEP9_CAEEL G5EEP9 Caenorhabditis elegans
G5EBP4_CAEEL G5EBP4 Caenorhabditis elegans
G5EFD6_CAEEL G5EFD6 Caenorhabditis elegans
41_DROME-4 Q9V8R9-4 Drosophila melanogaster
41_DROME-2 Q9V8R9-2 Drosophila melanogaster
41_DROME-6 Q9V8R9-6 Drosophila melanogaster
41_DROME-3 Q9V8R9-3 Drosophila melanogaster
41_DROME-5 Q9V8R9-5 Drosophila melanogaster
E3M8X8_CAERE E3M8X8 Caenorhabditis remanei