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Protein Domain : IPR004788

Name  Ribose 5-phosphate isomerase, type A Short Name  Ribose5P_isomerase_typA
Type  Family Description  Ribose 5-phosphate isomerase, also known as phosphoriboisomerase, catalyses the reversible conversion of D-ribose 5-phosphate to D-ribulose 5-phosphate, the first step in the non-oxidative branch of the pentose phosphate pathway []. This reaction enables ribose to be synthesized from sugars, as well as the recycling of sugars during the degradation of nucleotides. There are two unrelated types of ribose 5-phosphate isomerases: type A (RpiA) is the most common and is found in most organisms, while type B (RpiB) is restricted to specific eukaryotic and prokaryotic species. Escherichia coliproduces both RpiA and RpiB (also known as AlsB), although RpiA accounts for 99% of total RPI enzymes []. This entry represents type A (RpiA) enzymes found in eukaryotes (plants, Metazoa and fungi), bacteria and archaea.

Publication Counts Displayer

1 Child Features

DB identifier Name Short Name Type
IPR020672 Ribose-5-phosphate isomerase, type A, subgroup Ribose5P_isomerase_typA_subgr Family

0 Contains

3 Cross References

Identifier
Source . Name

Subject . Primary Identifier
PTHR11934 PANTHER IPR004788
PF06026 PFAM IPR004788
TIGR00021 TIGRFAMs IPR004788

3 Data Sets

Name URL
TrEMBL data set http://www.ebi.ac.uk/trembl/
InterPro data set  
InterPro GO Annotation data set  

0 Found In

2 GO Annotation


Subject . Secondary Identifier

Subject . Name

Subject . Symbol

Ontology Term . Identifier

Ontology Term . Name
Ribose 5-phosphate isomerase, type A   GO:0004751 ribose-5-phosphate isomerase activity
Ribose 5-phosphate isomerase, type A   GO:0009052 pentose-phosphate shunt, non-oxidative branch

2 Ontology Annotations


Subject . Secondary Identifier

Subject . Name

Subject . Symbol

Ontology Term . Identifier

Ontology Term . Name
Ribose 5-phosphate isomerase, type A   GO:0004751 ribose-5-phosphate isomerase activity
Ribose 5-phosphate isomerase, type A   GO:0009052 pentose-phosphate shunt, non-oxidative branch

0 Parent Features

13 Proteins

DB identifier Primary Accession
Organism . Name
FBpp0296955 Q8MLS2 Drosophila melanogaster
FBpp0276961 B5DZH8 Drosophila pseudoobscura
FBpp0167735 B4KS42 Drosophila mojavensis
FBpp0235799 B4LPM2 Drosophila virilis
FBpp0259289 B4P967 Drosophila yakuba
A8XPJ7_CAEBR A8XPJ7 Caenorhabditis briggsae
K7H9T2_CAEJA K7H9T2 Caenorhabditis japonica
K7H9T1_CAEJA K7H9T1 Caenorhabditis japonica
G0N5N6_CAEBE G0N5N6 Caenorhabditis brenneri
RPIA_CAEEL P41994 Caenorhabditis elegans
A9UNB7_DROME A9UNB7 Drosophila melanogaster
E3NWK8_CAERE E3NWK8 Caenorhabditis remanei
E3LSU4_CAERE E3LSU4 Caenorhabditis remanei