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Protein Domain : IPR002558

Name  I/LWEQ domain Short Name  ILWEQ_dom
Type  Domain Description  I/LWEQ domains bind to actin. It has been shown that the I/LWEQdomains from mouse talin and yeast Sla2pinteract with F-actin []. The domain has four conserved blocks, the name of the domain is derived from the initial conserved amino acid ofeach of the four blocks []. I/LWEQ domains can beplaced into four major groups based on sequence similarity:Metazoan talin.Dictyostelium discoideum(Slime mould) TalA/TalB.Metazoan Huntingtin-interacting protein-1 related (HIP1R) [].Saccharomyces cerevisiaeSla2p.

Publication Counts Displayer

0 Child Features

0 Contains

6 Cross References

Identifier
Source . Name

Subject . Primary Identifier
PF01608 PFAM IPR002558
PD011820 PRODOM IPR002558
PS50945 PROFILE IPR002558
SM00307 SMART IPR002558
G3DSA:1.20.1410.10 GENE3D IPR002558
SSF109885 SSF IPR002558

3 Data Sets

Name URL
TrEMBL data set http://www.ebi.ac.uk/trembl/
InterPro data set  
InterPro GO Annotation data set  

2 Found In

DB identifier Name Short Name Type
IPR015710 Talin-1 Talin-1 Family
IPR015711 Talin-2 Talin-2 Family

1 GO Annotation


Subject . Secondary Identifier

Subject . Name

Subject . Symbol

Ontology Term . Identifier

Ontology Term . Name
I/LWEQ domain   GO:0003779 actin binding

1 Ontology Annotations


Subject . Secondary Identifier

Subject . Name

Subject . Symbol

Ontology Term . Identifier

Ontology Term . Name
I/LWEQ domain   GO:0003779 actin binding

0 Parent Features

35 Proteins

DB identifier Primary Accession
Organism . Name
FBpp0075680 Q8MQJ8 Drosophila melanogaster
FBpp0075681 Q86BS5 Drosophila melanogaster
FBpp0293740 Q9VSL8 Drosophila melanogaster
FBpp0293741 M9NDM3 Drosophila melanogaster
FBpp0305319 M9PBW9 Drosophila melanogaster
FBpp0305320 M9PEJ8 Drosophila melanogaster
FBpp0277245 Q29FI8 Drosophila pseudoobscura
FBpp0161141 B4KY13 Drosophila mojavensis
FBpp0162125 B4KZ53 Drosophila mojavensis
FBpp0227466 B4LEJ9 Drosophila virilis
FBpp0228216 B4LGF9 Drosophila virilis
FBpp0265109 B4PGU6 Drosophila yakuba
FBpp0265762 B4PG07 Drosophila yakuba
A8XLZ9_CAEBR A8XLZ9 Caenorhabditis briggsae
A8Y1N6_CAEBR A8Y1N6 Caenorhabditis briggsae
B6IM09_CAEBR B6IM09 Caenorhabditis briggsae
K7HYS4_CAEJA K7HYS4 Caenorhabditis japonica
H2WVP0_CAEJA H2WVP0 Caenorhabditis japonica
K7H706_CAEJA K7H706 Caenorhabditis japonica
K7H707_CAEJA K7H707 Caenorhabditis japonica
G0MNX4_CAEBE G0MNX4 Caenorhabditis brenneri
G0MNX3_CAEBE G0MNX3 Caenorhabditis brenneri
G0MGA1_CAEBE G0MGA1 Caenorhabditis brenneri
SLAP2_CAEEL Q02328 Caenorhabditis elegans
SLAP2_CAEEL-2 Q02328-2 Caenorhabditis elegans
G5EGK1_CAEEL G5EGK1 Caenorhabditis elegans
Q95XN3_CAEEL Q95XN3 Caenorhabditis elegans
W6SBK6_CAEEL W6SBK6 Caenorhabditis elegans
G4S9F5_CAEEL G4S9F5 Caenorhabditis elegans
Q960C2_DROME Q960C2 Drosophila melanogaster