modENCODE |  Help |  blog

Protein Domain : IPR000426

Name  Proteasome alpha-subunit, N-terminal domain Short Name  Proteasome_asu_N
Type  Domain Description  The proteasome (or macropain) () [, , , , ]is a eukaryotic andarchaeal multicatalytic proteinase complex that seems to be involved inan ATP/ubiquitin-dependent nonlysosomal proteolytic pathway. In eukaryotes theproteasome is composed of about 28 distinct subunits which form a highlyordered ring-shaped structure (20S ring) of about 700 kDa.Most proteasome subunits can be classified on the basis of sequence similarities into two groups, alpha (A) and beta (B).Subunits that belong to the A group are proteins of from 210 to 290 amino acids. They are classified as non-peptidase homologues in MEROPS peptidase family T1 (clan PB(T)). This entry represents an N-terminal domain conserved in the A subunits of the proteasome complex.

Publication Counts Displayer

0 Child Features

0 Contains

3 Cross References

Identifier
Source . Name

Subject . Primary Identifier
PF10584 PFAM IPR000426
PS00388 PROSITE IPR000426
SM00948 SMART IPR000426

3 Data Sets

Name URL
TrEMBL data set http://www.ebi.ac.uk/trembl/
InterPro data set  
InterPro GO Annotation data set  

1 Found In

DB identifier Name Short Name Type
IPR019982 Proteasome alpha subunit, archaeal Proteasome_asu_arc Family

3 GO Annotation


Subject . Secondary Identifier

Subject . Name

Subject . Symbol

Ontology Term . Identifier

Ontology Term . Name
Proteasome alpha-subunit, N-terminal domain   GO:0004175 endopeptidase activity
Proteasome alpha-subunit, N-terminal domain   GO:0006511 ubiquitin-dependent protein catabolic process
Proteasome alpha-subunit, N-terminal domain   GO:0019773 proteasome core complex, alpha-subunit complex

3 Ontology Annotations


Subject . Secondary Identifier

Subject . Name

Subject . Symbol

Ontology Term . Identifier

Ontology Term . Name
Proteasome alpha-subunit, N-terminal domain   GO:0004175 endopeptidase activity
Proteasome alpha-subunit, N-terminal domain   GO:0006511 ubiquitin-dependent protein catabolic process
Proteasome alpha-subunit, N-terminal domain   GO:0019773 proteasome core complex, alpha-subunit complex

0 Parent Features

104 Proteins

DB identifier Primary Accession
Organism . Name
FBpp0082062 P40301 Drosophila melanogaster
FBpp0071451 P18053 Drosophila melanogaster
FBpp0083336 Q24178 Drosophila melanogaster
FBpp0080028 Q9VK14 Drosophila melanogaster
FBpp0085100 Q9VA12 Drosophila melanogaster
FBpp0089041 Q9V5C6 Drosophila melanogaster
FBpp0079538 P12881 Drosophila melanogaster
FBpp0086066 Q95083 Drosophila melanogaster
FBpp0087968 Q9XZJ4 Drosophila melanogaster
FBpp0072257 Q27575 Drosophila melanogaster
FBpp0073989 P22769 Drosophila melanogaster
FBpp0281088 B5DWY5 Drosophila pseudoobscura
FBpp0287416 Q29KI2 Drosophila pseudoobscura
FBpp0273817 Q29GE7 Drosophila pseudoobscura
FBpp0275922 B5E188 Drosophila pseudoobscura
FBpp0277614 Q291H6 Drosophila pseudoobscura
FBpp0277951 Q28ZN7 Drosophila pseudoobscura
FBpp0278676 Q28X36 Drosophila pseudoobscura
FBpp0278728 B5DZ68 Drosophila pseudoobscura
FBpp0279104 B5DHA3 Drosophila pseudoobscura
FBpp0280573 B5DIE8 Drosophila pseudoobscura
FBpp0283406 Q29B24 Drosophila pseudoobscura
FBpp0287663 B5DJB3 Drosophila pseudoobscura
FBpp0308081 N6VF87 Drosophila pseudoobscura
FBpp0268584 B4P245 Drosophila yakuba
FBpp0160427 B4L7P9 Drosophila mojavensis
FBpp0165268 B4L735 Drosophila mojavensis
FBpp0166538 B4KLA0 Drosophila mojavensis
FBpp0167474 B4KJ15 Drosophila mojavensis
FBpp0167504 B4KJK6 Drosophila mojavensis