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Protein Domain : IPR000159

Name  Ras-association Short Name  Ras-assoc
Type  Domain Description  Proteins with this domain are mostly RasGTP effectors and include guanine-nucleotide releasing factor in mammals []. This factor stimulates the dissociation of GDP from the Ras-related RALA and RALB GTPases, which allows GTP binding and activation of the GTPases. It interacts and acts as an effector molecule for R-ras, K-Ras and Rap [].The domain is also present in a number of other proteins among them the sexual differentiation protein in yeast that is essential for mating and meiosis and yeast adenylate cyclase. These proteins contain repeated leucine-rich (LRR) segments.

Publication Counts Displayer

0 Child Features

0 Contains

3 Cross References

Identifier
Source . Name

Subject . Primary Identifier
PF00788 PFAM IPR000159
PS50200 PROFILE IPR000159
SM00314 SMART IPR000159

3 Data Sets

Name URL
TrEMBL data set http://www.ebi.ac.uk/trembl/
InterPro data set  
InterPro GO Annotation data set  

1 Found In

DB identifier Name Short Name Type
IPR015758 Ral guanine nucleotide dissociation stimulator RalGDS Family

1 GO Annotation


Subject . Secondary Identifier

Subject . Name

Subject . Symbol

Ontology Term . Identifier

Ontology Term . Name
Ras-association   GO:0007165 signal transduction

1 Ontology Annotations


Subject . Secondary Identifier

Subject . Name

Subject . Symbol

Ontology Term . Identifier

Ontology Term . Name
Ras-association   GO:0007165 signal transduction

0 Parent Features

185 Proteins

DB identifier Primary Accession
Organism . Name
FBpp0289316 B7Z026 Drosophila melanogaster
FBpp0289315 B7Z025 Drosophila melanogaster
FBpp0078879 Q9VMF3 Drosophila melanogaster
FBpp0083799 Q9VCQ7 Drosophila melanogaster
FBpp0074574 Q8IQW0 Drosophila melanogaster
FBpp0074573 Q9VWB7 Drosophila melanogaster
FBpp0083885 Q9VCF2 Drosophila melanogaster
FBpp0083886 Q7KS35 Drosophila melanogaster
FBpp0075535 Q9U4U5 Drosophila melanogaster
FBpp0075536 Q86BI2 Drosophila melanogaster
FBpp0070808 Q9W486 Drosophila melanogaster
FBpp0078789 Q9VML8 Drosophila melanogaster
FBpp0084272 Q9VBP2 Drosophila melanogaster
FBpp0289752 Q9VN82 Drosophila melanogaster
FBpp0111548 Q7K3Z6 Drosophila melanogaster
FBpp0112304 A8JR94 Drosophila melanogaster
FBpp0111600 Q8MQW8 Drosophila melanogaster
FBpp0288987 Q8IPP4 Drosophila melanogaster
FBpp0288988 Q8IPP3 Drosophila melanogaster
FBpp0290185 Q7KS34 Drosophila melanogaster
FBpp0303219 M9PCE9 Drosophila melanogaster
FBpp0292964 M9MSQ5 Drosophila melanogaster
FBpp0308608 F3YD98 Drosophila melanogaster
FBpp0300585 Q296I9 Drosophila pseudoobscura
FBpp0291896 I5AMS5 Drosophila pseudoobscura
FBpp0274406 Q2M017 Drosophila pseudoobscura
FBpp0272337 Q29FS0 Drosophila pseudoobscura
FBpp0284459 Q296A4 Drosophila pseudoobscura
FBpp0300778 I5APD5 Drosophila pseudoobscura
FBpp0273156 Q29GU7 Drosophila pseudoobscura