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Protein Domain : IPR000152

Name  EGF-type aspartate/asparagine hydroxylation site Short Name  EGF-type_Asp/Asn_hydroxyl_site
Type  PTM Description  Post-translational hydroxylation of aspartic acid or asparagine []to formerythro-beta-hydroxyaspartic acid or erythro-beta-hydroxyasparagine has beenidentified in a number of proteins with domains homologous to epidermal growthfactor (EGF). Examples of such proteins are the blood coagulation proteinfactors VII, IX and X, proteins C, S, and Z, the LDL receptor, thrombomodulin,etc. Based on sequence comparisons of the EGF-homology region that containshydroxylated Asp or Asn, a consensus sequence has been identified that seemsto be required by the hydroxylase(s).
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Publication Counts Displayer

0 Child Features

0 Contains

1 Cross References

Identifier
Source . Name
Subject . Primary Identifier
PS00010 PROSITE IPR000152

2 Data Sets

Name URL
TrEMBL data set http://www.ebi.ac.uk/trembl/
InterPro data set  

10 Found In

DB identifier Name Short Name Type
IPR000742 Epidermal growth factor-like domain EG-like_dom Domain
IPR001881 EGF-like calcium-binding domain EGF-like_Ca-bd_dom Domain
IPR015446 Bone morphogenetic protein 1/tolloid-like protein BMP_1/tolloid-like Family
IPR008297 Notch Notch Family
IPR011398 Fibrillin/Microneme protein4 FBN/EtMIC4 Family
IPR017048 Fibulin-1 Fibulin-1 Family
IPR001491 Thrombomodulin Thrombomodulin Family
IPR003056 GPCR, family 2, CD97 antigen GPCR_2_CD97 Family
IPR016317 Pro-epidermal growth factor Pro-epidermal_GF Family
IPR016316 Complement component C1q/Thrombomodulin CD93/CD141 Family

0 GO Annotation

0 Ontology Annotations

0 Parent Features

439 Proteins

DB identifier Primary Accession
Organism . Name
FBpp0293675 M9NE82 Drosophila melanogaster
FBpp0293671 M9NER8 Drosophila melanogaster
FBpp0293672 M9NCR4 Drosophila melanogaster
FBpp0304620 M9PC41 Drosophila melanogaster
FBpp0304623 M9PBZ0 Drosophila melanogaster
FBpp0304622 M9PB30 Drosophila melanogaster
FBpp0304632 M9PB32 Drosophila melanogaster
FBpp0304630 M9PC48 Drosophila melanogaster
FBpp0304631 M9PEI7 Drosophila melanogaster
FBpp0304625 M9PC45 Drosophila melanogaster
FBpp0304626 M9PEI1 Drosophila melanogaster
FBpp0304621 M9PEH5 Drosophila melanogaster
FBpp0304624 M9PCJ6 Drosophila melanogaster
FBpp0304629 M9PCJ8 Drosophila melanogaster
FBpp0304627 M9PB31 Drosophila melanogaster
FBpp0304628 M9PBZ4 Drosophila melanogaster
FBpp0099719 Q4ABE9 Drosophila melanogaster
FBpp0099720 Q4ABE8 Drosophila melanogaster
FBpp0288558 Q9VM55 Drosophila melanogaster
FBpp0291372 E1JHA6 Drosophila melanogaster
FBpp0087438 A1Z877 Drosophila melanogaster
FBpp0073715 P98163 Drosophila melanogaster
FBpp0073147 Q95RQ1 Drosophila melanogaster
FBpp0302585 L0MPM5 Drosophila melanogaster
FBpp0302583 L0MLI5 Drosophila melanogaster
FBpp0306415 L0MPW2 Drosophila melanogaster
FBpp0083153 P10041 Drosophila melanogaster
FBpp0070483 P07207 Drosophila melanogaster
FBpp0084069 Q9VC47 Drosophila melanogaster
FBpp0073931 Q9VXM0 Drosophila melanogaster




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