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Protein Domain : IPR006620

Name  Prolyl 4-hydroxylase, alpha subunit Short Name  Pro_4_hyd_alph
Type  Domain Description  Mammalian prolyl 4-hydroxylase alpha catalyses the posttranslational formation of4- hydroxyproline in -xaa-pro-gly-sequences incollagens and other proteins.Prokaryoticenzymes mightcatalyse hydroxylation of antibiotic peptides. These are2-oxoglutarate-dependent dioxygenases,requiring 2-oxoglutarate and dioxygen as cosubstrates and ferrous iron as acofactor [].

Publication Counts Displayer

0 Child Features

0 Contains

1 Cross References

Identifier
Source . Name

Subject . Primary Identifier
SM00702 SMART IPR006620

3 Data Sets

Name URL
TrEMBL data set http://www.ebi.ac.uk/trembl/
InterPro data set  
InterPro GO Annotation data set  

1 Found In

DB identifier Name Short Name Type
IPR001006 Procollagen-lysine 5-dioxygenase Procol_lys_dOase Family

4 GO Annotation


Subject . Secondary Identifier

Subject . Name

Subject . Symbol

Ontology Term . Identifier

Ontology Term . Name
Prolyl 4-hydroxylase, alpha subunit   GO:0005506 iron ion binding
Prolyl 4-hydroxylase, alpha subunit   GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
Prolyl 4-hydroxylase, alpha subunit   GO:0031418 L-ascorbic acid binding
Prolyl 4-hydroxylase, alpha subunit   GO:0055114 oxidation-reduction process

4 Ontology Annotations


Subject . Secondary Identifier

Subject . Name

Subject . Symbol

Ontology Term . Identifier

Ontology Term . Name
Prolyl 4-hydroxylase, alpha subunit   GO:0005506 iron ion binding
Prolyl 4-hydroxylase, alpha subunit   GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
Prolyl 4-hydroxylase, alpha subunit   GO:0031418 L-ascorbic acid binding
Prolyl 4-hydroxylase, alpha subunit   GO:0055114 oxidation-reduction process

1 Parent Features

DB identifier Name Short Name Type
IPR005123 Oxoglutarate/iron-dependent dioxygenase Oxoglu/Fe-dep_dioxygenase Domain

187 Proteins

DB identifier Primary Accession
Organism . Name
FBpp0290184 Q9VA52 Drosophila melanogaster
FBpp0110159 Q0KHY6 Drosophila melanogaster
FBpp0085046 Q8IMI2 Drosophila melanogaster
FBpp0293245 Q9VVQ6 Drosophila melanogaster
FBpp0085033 Q9VA50 Drosophila melanogaster
FBpp0085032 Q8T5S8 Drosophila melanogaster
FBpp0085029 Q961I8 Drosophila melanogaster
FBpp0099996 Q8MSK0 Drosophila melanogaster
FBpp0085019 Q9VA60 Drosophila melanogaster
FBpp0085050 Q9VA64 Drosophila melanogaster
FBpp0075918 Q9VTH0 Drosophila melanogaster
FBpp0085047 Q9VA61 Drosophila melanogaster
FBpp0308258 Q9I7H9 Drosophila melanogaster
FBpp0085015 Q9I7H5 Drosophila melanogaster
FBpp0085051 Q9VA65 Drosophila melanogaster
FBpp0110158 Q0KHY7 Drosophila melanogaster
FBpp0085017 Q4V443 Drosophila melanogaster
FBpp0085012 Q9VA69 Drosophila melanogaster
FBpp0085048 Q9VA63 Drosophila melanogaster
FBpp0289601 Q9VHU7 Drosophila melanogaster
FBpp0310869 Q9VVQ4 Drosophila melanogaster
FBpp0303836 Q9VVQ9 Drosophila melanogaster
FBpp0289328 Q8IQS7 Drosophila melanogaster
FBpp0289329 Q9VVQ7 Drosophila melanogaster
FBpp0111465 A8DYR4 Drosophila melanogaster
FBpp0306391 Q8SX21 Drosophila melanogaster
FBpp0306389 Q8I0C2 Drosophila melanogaster
FBpp0306390 Q9VN98 Drosophila melanogaster
FBpp0289326 Q9VVQ5 Drosophila melanogaster
FBpp0288181 B5DV23 Drosophila pseudoobscura