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Protein Domain : IPR028889

Name  Ubiquitin carboxyl-terminal hydrolase-like domain Short Name  UCH/PAN2
Type  Domain Description  Ubiquitin carboxyl-terminal hydrolases (UCH) () []are thiol proteases that recognise and hydrolyse the peptide bond at the C-terminal glycine of ubiquitin. These enzymes are involved in the processing of poly-ubiquitin precursors as well as that of ubiquinated proteins. The deubiquitinsing proteases can be split into 2 size ranges, 20-30 kDa() and 100-200 kDa []: the second class consist of large proteins (800 to 2000 residues) that belong to the peptidase family C19, and this group is currently represented by yeast UBP1 []. This entry represents a USP (ubiquitin carboxyl-terminal) domain found in UCHs of the UBP1 group and in PAN2 (inactive ubiquitin carboxyl-terminal hydrolase 52).

Publication Counts Displayer

3 Child Features

DB identifier Name Short Name Type
IPR001394 Peptidase C19, ubiquitin carboxyl-terminal hydrolase Peptidase_C19_UCH Domain
IPR028881 PAB-dependent poly(A)-specific ribonuclease subunit PAN2 PAN2 Domain
IPR028890 Ubiquitin-specific peptidase-like, SUMO isopeptidase Peptidase_C98 Domain

0 Contains

1 Cross References

Identifier
Source . Name

Subject . Primary Identifier
PS50235 PROFILE IPR028889

2 Data Sets

Name URL
Swiss-Prot data set http://ca.expasy.org/sprot
InterPro data set  

0 Found In

0 GO Annotation

0 Ontology Annotations

0 Parent Features

303 Proteins

DB identifier Primary Accession
Organism . Name
FBpp0087062 Q7JQI1 Drosophila melanogaster
FBpp0072276 Q9W117 Drosophila melanogaster
FBpp0072976 Q9VZU7 Drosophila melanogaster
FBpp0070793 Q9W462 Drosophila melanogaster
FBpp0076806 Q9VRP5 Drosophila melanogaster
FBpp0305464 M9PDK3 Drosophila melanogaster
FBpp0072486 Q9W0L7 Drosophila melanogaster
FBpp0086664 Q7JW61 Drosophila melanogaster
FBpp0070739 Q9W4C3 Drosophila melanogaster
FBpp0073474 Q9VYQ8 Drosophila melanogaster
FBpp0085202 P55824 Drosophila melanogaster
FBpp0076802 Q24574 Drosophila melanogaster
FBpp0074414 Q9VWP1 Drosophila melanogaster
FBpp0084048 Q9VC56 Drosophila melanogaster
FBpp0084047 Q7KS15 Drosophila melanogaster
FBpp0083419 Q9VDD8 Drosophila melanogaster
FBpp0293257 H1UUC2 Drosophila melanogaster
FBpp0077042 Q8IQ26 Drosophila melanogaster
FBpp0077038 Q9VR54 Drosophila melanogaster
FBpp0077041 Q8IQ27 Drosophila melanogaster
FBpp0087735 A1Z7K9 Drosophila melanogaster
FBpp0079650 Q9VKZ8 Drosophila melanogaster
FBpp0304460 M9PG46 Drosophila melanogaster
FBpp0304461 M9PFZ0 Drosophila melanogaster
FBpp0304458 M9PD06 Drosophila melanogaster
FBpp0304459 M9PFQ1 Drosophila melanogaster
FBpp0290056 Q8I077 Drosophila melanogaster
FBpp0111713 Q1W9Q0 Drosophila melanogaster
FBpp0083704 Q9VCT9 Drosophila melanogaster
FBpp0300237 I5ANW7 Drosophila pseudoobscura