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Protein Domain : IPR012446

Name  Calcium release-activated calcium channel protein Short Name  CRAC_channel
Type  Family Description  This entry includes Drosophila Orai and human Orai1, Orai2 and Orai3. ORAI-1 GFP reporters are co-expressed with STIM-1 (ER CA(2+) sensors) in the gonad and intestine. The protein has four predicted transmembrane domains with a highly conserved region between TM2 ad TM3. This conserved domain is thought to function in channel regulation. ORAI1-related proteins are required for the production of the calcium channel, CRAC, along with STIM1-related proteins [].

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0 Child Features

0 Contains

1 Cross References

Source . Name

Subject . Primary Identifier
PF07856 PFAM IPR012446

2 Data Sets

Name URL
Swiss-Prot data set
InterPro data set  

0 Found In

0 GO Annotation

0 Ontology Annotations

0 Parent Features

16 Proteins

DB identifier Primary Accession
Organism . Name
FBpp0085976 Q9U6B8 Drosophila melanogaster
FBpp0113106 B7YZJ7 Drosophila melanogaster
FBpp0308200 N6W572 Drosophila pseudoobscura
FBpp0308199 N6V920 Drosophila pseudoobscura
FBpp0168337 B4KQU4 Drosophila mojavensis
FBpp0236669 B4LL00 Drosophila virilis
FBpp0256917 B4P522 Drosophila yakuba
ORAI_CAEBR Q616J1 Caenorhabditis briggsae
H2VQ25_CAEJA H2VQ25 Caenorhabditis japonica
G0MYZ1_CAEBE G0MYZ1 Caenorhabditis brenneri
ORAI_CAEEL Q09232 Caenorhabditis elegans
B6VQ32_CAEEL B6VQ32 Caenorhabditis elegans
CRCM1_DROME-4 Q9U6B8-4 Drosophila melanogaster
CRCM1_DROME-3 Q9U6B8-3 Drosophila melanogaster
CRCM1_DROME-2 Q9U6B8-2 Drosophila melanogaster
E3MLB4_CAERE E3MLB4 Caenorhabditis remanei