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Protein Domain : IPR029061

Name  Thiamin diphosphate-binding fold Short Name  THDP-binding
Type  Domain Description  This entry represents the thiamin diphosphate-binding fold found in pyruvate dehydrogenases, branched chain alpha-keto acid decarboxylases, phosphoketolases and the pyrimidine binding region of transketolases []. There are two different functional modules of this fold: pyridine-binding (Pyr) and pyrophosphate-binding (PP) modules. Two Pyr and two PP modules can assemble together in a conserved heterotetrameric core that binds two THDP coenzyme molecules.

Publication Counts Displayer

0 Child Features

0 Contains

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
G3DSA:3.40.50.970 GENE3D IPR029061
SSF52518 SSF IPR029061

2 Data Sets

Name URL
Swiss-Prot data set http://ca.expasy.org/sprot
InterPro data set  

0 Found In

0 GO Annotation

0 Ontology Annotations

0 Parent Features

137 Proteins

DB identifier Primary Accession
Organism . Name
FBpp0075028 Q9VVC5 Drosophila melanogaster
FBpp0072631 Q95T35 Drosophila melanogaster
FBpp0072633 Q0E8J6 Drosophila melanogaster
FBpp0070679 Q7KVX1 Drosophila melanogaster
FBpp0070677 Q9W4H6 Drosophila melanogaster
FBpp0070678 Q7YU05 Drosophila melanogaster
FBpp0075027 Q8IQQ0 Drosophila melanogaster
FBpp0070680 Q9W4H4 Drosophila melanogaster
FBpp0291602 A8QHW8 Drosophila melanogaster
FBpp0291601 Q7PLE6 Drosophila melanogaster
FBpp0081545 Q9VHB8 Drosophila melanogaster
FBpp0084735 Q7K5K3 Drosophila melanogaster
FBpp0084737 Q8IML6 Drosophila melanogaster
FBpp0074898 Q9VVP4 Drosophila melanogaster
FBpp0085630 Q7K3B7 Drosophila melanogaster
FBpp0081370 Q9VHN7 Drosophila melanogaster
FBpp0081372 Q7KSU6 Drosophila melanogaster
FBpp0085117 Q9VA02 Drosophila melanogaster
FBpp0290113 E1JHW5 Drosophila melanogaster
FBpp0111773 A8JNU6 Drosophila melanogaster
FBpp0288163 B5DSC2 Drosophila pseudoobscura
FBpp0281830 B5DWE4 Drosophila pseudoobscura
FBpp0284588 Q295J7 Drosophila pseudoobscura
FBpp0273573 Q29IF7 Drosophila pseudoobscura
FBpp0273575 Q29IF6 Drosophila pseudoobscura
FBpp0280005 B5DIC8 Drosophila pseudoobscura
FBpp0293043 I5AMT5 Drosophila pseudoobscura
FBpp0282990 Q29CE4 Drosophila pseudoobscura
FBpp0286887 Q29E02 Drosophila pseudoobscura
FBpp0286941 Q29DU3 Drosophila pseudoobscura