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Protein Domain : IPR001017

Name  Dehydrogenase, E1 component Short Name  DH_E1
Type  Domain Description  This entry includes a number of dehydrogenases all of which use thiaminepyrophosphate as a cofactor and are members of a multienzyme complex.Pyruvate dehydrogenase (), a component of the multienzymepyruvate dehydrogenase complex; 2-oxoglutarate dehydrogenase (),a component of the multienzyme 2-oxoglutarate dehydrogenase which containsmultiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1),dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3);and 2-oxoisovalerate dehydrogenase (), a component of the multienzymebranched-chain alpha-keto dehydrogenase complex all belong to this family.

Publication Counts Displayer

0 Child Features

0 Contains

1 Cross References

Identifier
Source . Name

Subject . Primary Identifier
PF00676 PFAM IPR001017

3 Data Sets

Name URL
Swiss-Prot data set http://ca.expasy.org/sprot
InterPro data set  
InterPro GO Annotation data set  

3 Found In

DB identifier Name Short Name Type
IPR011603 2-oxoglutarate dehydrogenase, E1 component 2oxoglutarate_DH_E1 Family
IPR017597 Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit, subgroup y Pyrv_DH_E1_asu_subgrp-y Family
IPR017596 Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit subgroup x Pyrv_DH_E1_asu_subgrp-x Family

2 GO Annotation


Subject . Secondary Identifier

Subject . Name

Subject . Symbol

Ontology Term . Identifier

Ontology Term . Name
Dehydrogenase, E1 component   GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
Dehydrogenase, E1 component   GO:0008152 metabolic process

2 Ontology Annotations


Subject . Secondary Identifier

Subject . Name

Subject . Symbol

Ontology Term . Identifier

Ontology Term . Name
Dehydrogenase, E1 component   GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
Dehydrogenase, E1 component   GO:0008152 metabolic process

0 Parent Features

68 Proteins

DB identifier Primary Accession
Organism . Name
FBpp0075028 Q9VVC5 Drosophila melanogaster
FBpp0072631 Q95T35 Drosophila melanogaster
FBpp0072633 Q0E8J6 Drosophila melanogaster
FBpp0070679 Q7KVX1 Drosophila melanogaster
FBpp0070677 Q9W4H6 Drosophila melanogaster
FBpp0070678 Q7YU05 Drosophila melanogaster
FBpp0075027 Q8IQQ0 Drosophila melanogaster
FBpp0070680 Q9W4H4 Drosophila melanogaster
FBpp0081545 Q9VHB8 Drosophila melanogaster
FBpp0085117 Q9VA02 Drosophila melanogaster
FBpp0290113 E1JHW5 Drosophila melanogaster
FBpp0111773 A8JNU6 Drosophila melanogaster
FBpp0284588 Q295J7 Drosophila pseudoobscura
FBpp0273573 Q29IF7 Drosophila pseudoobscura
FBpp0273575 Q29IF6 Drosophila pseudoobscura
FBpp0280005 B5DIC8 Drosophila pseudoobscura
FBpp0293043 I5AMT5 Drosophila pseudoobscura
FBpp0282990 Q29CE4 Drosophila pseudoobscura
FBpp0286887 Q29E02 Drosophila pseudoobscura
FBpp0286941 Q29DU3 Drosophila pseudoobscura
FBpp0161685 B4KYN6 Drosophila mojavensis
FBpp0162486 B4KW84 Drosophila mojavensis
FBpp0163341 B4KK39 Drosophila mojavensis
FBpp0164128 B4L471 Drosophila mojavensis
FBpp0164127 B4L472 Drosophila mojavensis
FBpp0171538 B4K6G8 Drosophila mojavensis
FBpp0173304 B4K658 Drosophila mojavensis
FBpp0224925 B4M5V2 Drosophila virilis
FBpp0233359 B4M3J0 Drosophila virilis
FBpp0233360 B4M3I9 Drosophila virilis